Pharmacological effects of venlafaxine, a new antidepressant, given repeatedly, on the α1-adrenergic, dopamine and serotonin systems

被引：0
|
作者：
J. Maj
Z. Rogóż
机构：
[1] Institute of Pharmacology,
[2] Polish Academy of Sciences,undefined
[3] Kraków,undefined
[4] Poland,undefined
来源：
Journal of Neural Transmission | 1999年 / 106卷
关键词：
Keywords: Venlafaxine; repeated treatment; adaptive changes in neurotransmitter systems.;
D O I：
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学科分类号：
摘要：
Venlafaxine (VEN) is a representative of a new class of antidepressants (SNRIs) which inhibit selectively the uptake of serotonin and noradrenaline, but – in contrast to tricyclics – show no affinity for neurotransmitter receptors. The present study was aimed at determining whether repeated VEN (given twice daily for 14 days) induced adaptive changes in the α1-adrenergic, dopamine and serotonin systems, similar to those reported by us earlier for tricyclic antidepressants.
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页码：197 / 211
页数：14
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