Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML

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作者
Maria Solovey
Ying Wang
Christian Michel
Klaus H. Metzeler
Tobias Herold
Joachim R. Göthert
Volker Ellenrieder
Elisabeth Hessmann
Stefan Gattenlöhner
Andreas Neubauer
Dinko Pavlinic
Vladimir Benes
Oliver Rupp
Andreas Burchert
机构
[1] Philipps University Marburg,Department of Hematology, Oncology and Immunology, University Hospital Giessen and Marburg, Campus Marburg
[2] LMU Munich,Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital
[3] University Hospital Essen,Department of Hematology
[4] University Hospital Goettingen,Department of Gastroenterology
[5] Justus-Liebig-University,Institute of Pathology
[6] EMBL Heidelberg ,Genomics Core Facility
[7] University Giessen,Department of Bioinformatics and Systems Biology
关键词
FLT3; Acute myeloid leukemia; Hematopoietic stem cells; NFATC1; Drug resistance;
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