Condensation of 1-substituted 1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]-indol-2-one derivatives with aromatic aldehydes

被引：0
|
作者：
Sackus A. [1 ]
Amankaviciene V. [1 ]
机构：
[1] Department of Organic Chemistry, Faculty of Chemical Technology, Kaunas University of Technology
来源：
Chemistry of Heterocyclic Compounds | 2002年 / 38卷 / 07期
关键词：
1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one; 9a-(2-phenylethenyl)-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one; Alkylation; Condensation;
D O I：
10.1023/A:1020685704961
中图分类号：
学科分类号：
摘要：
Condensation of 1-alkyl-, 1-allyl-, and 1-benzyl-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-ones with benzaldehydes in acetic acid and subsequent treatment of the reaction mixture with potassium hydroxide afforded 1-substituted 9a-(2-phenylethenyl)-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one derivatives. 1-Methyl- and 1-ethyl-9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo [1,2-a]indol-2-ones were synthesized by alkylation of 9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a] indol-2-one with methyl- and ethyl iodides in DMF in the presence of a strong base.
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页码：822 / 827
页数：5
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