Synthesis and intramolecular cyclization of some derivatives of 3-[(2,3-dihydro-1Н-1,5-benzodiazepin-4-yl)methylidene]indolin-2-one

被引：0
|
作者：
K. V. Maslov
A. N. Andin
O. Yu. Slabko
机构：
[1] Far-Eastern Federal University,
来源：
Russian Journal of Organic Chemistry | 2016年 / 52卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Isatin and its 5-bromo derivative react with о-phenylenediamine and acetone in formic acid; products of this three-component condensation were isolated as perchlorates, from which for the first time bases were obtained, derivatives of 3-[(2,3-dihydro-1Н-1,5-benzodiazepin-4-yl)methylidene]indolin-2-one. The reduction of these derivatives with sodium cyanoborohydride is followed by intramolecular cyclization affording a bridged 2,3,4,5-tetrahydro-1,4-methano-1Н-1,5-benzodiazepine system.
引用
收藏
页码：1657 / 1660
页数：3
相关论文
共 50 条
  • [21] Convenient synthesis of [1,5-c]quinazolo-2,3-dihydro-1,2,4,3-triazaphospholes and [1,5-c]quinazolo-2,3-dihydro-1,2,4,3-triazaphosphole-3-sulfides
    Abderrahim, Raoudha
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2007, 182 (04) : 893 - 897
  • [22] Synthesis of 4-pyridyl-2,3-dihydro1h-1,5-benzodiazepin-2-ones
    Bozhanov V.I.
    Ivonin S.P.
    Chemistry of Heterocyclic Compounds, 2002, 38 (09) : 1098 - 1103
  • [23] Ethyl 2-(2-oxo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-1-yl)acetate
    Ballo, Daouda
    Ahabchane, Noureddine Hamou
    Zouihri, Hafid
    Essassi, El Mokhtar
    Ng, Seik Weng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O2070 - U1663
  • [24] SYNTHESIS OF 4-STYRYL-2,3-DIHYDRO-1H-1,5-BENZODIAZEPIN-2-ONES
    SOLOMKO, ZF
    GAPONOV, AA
    AVRAMENKO, VI
    KHMEL, MP
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1987, (11): : 1560 - 1562
  • [25] Synthesis and Application of 3-(4-Hydroxyphenylimino)indolin-2-one as Corrosion Inhibitor
    Hao, Hua-Rui
    Zhao, Wei
    Zhang, Jie
    Miao, Yan-Qing
    Zhang, Zhi-Fang
    JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2015, 37 (06): : 1124 - 1129
  • [26] CYANO-(1-METHYLBENZIMIDAZOL-2-YL)THIOACETANILIDE IN THE SYNTHESIS OF 2,3-DIHYDRO-1,3,4-THIADIAZOLE DERIVATIVES
    HASSANEEN, HM
    HARHASH, AHE
    ABOUNADA, NM
    ABDALLAH, TA
    ALGHARIB, MS
    JOURNAL OF CHEMICAL RESEARCH-S, 1993, (05): : 194 - 195
  • [27] A novel receptor ligand: 1-(1-cyclooctylpiperidin-4-yl)indolin-2-one
    Parrish, DA
    Deschamps, JR
    Jiang, FM
    Zaveri, NT
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2004, 60 : O1571 - O1572
  • [28] Crystal structure of 3-{5-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2-one ethanol monosolvate
    Rahman, Md. Lutfor
    Kulkarni, Ajaykumar D.
    Yusoff, Mashitah Mohd.
    Kwong, Huey Chong
    Quah, Ching Kheng
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2016, 72 : 283 - +
  • [29] Facile synthesis of 2-benzoyl-6-hydroxy-3-methyl-5-(2-substituted-2, 3-dihydro-1H-1,5-benzodiazepin-4-yl)benzo[B]furans.
    Reddy, KVV
    Ashok, D
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 219 : U185 - U186
  • [30] 1-benzyl-3-(2-(pyridin-2-yl)hydrazono)indolin-2-one
    Rachid, Bouhfid
    Joly, Nicolas
    Lequart, Vincent
    Martin, Patrick
    Massoui, Mohamed
    Essassi, El Mokhtar
    MOLBANK, 2007, (02)
12345