Mechanisms of Responses of Systemic Circulation: Role of the Endothelial Factor of Vascular Tone Control

被引：0
|
作者：
L. I. Osadchii
T. V. Balueva
I. V. Sergeev
机构：
[1] Russian Academy of Sciences,Pavlov Institute of Physiology
来源：
Biology Bulletin of the Russian Academy of Sciences | 2004年 / 31卷
关键词：
Blood Pressure; Experimental Data; Cardiac Output; Systemic Circulation; Orthostatic Hypotension;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Experimental data on the effect of NO synthase inhibition on hemodynamic changes (blood pressure, cardiac output, and peripheral resistance) induced by an increased (polyglucin infusion) or decreased (orthostasis) cardiac output are presented. Under conditions of NO synthase inhibition, the pressor effects of polyglucin and orthostatic hypotension increased by 70 and 72%, respectively. The response of peripheral resistance had a similar trend. Significance of NO secretion by vascular endothelium for the development of systemic hemodynamic responses is proposed.
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页码：277 / 280
页数：3
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