Mechanisms of responses of systemic circulation: Role of the endothelial factor of vascular tone control

被引：0
|
作者：
Osadchii, LI [1 ]
Balueva, TV [1 ]
Sergeev, IV [1 ]
机构：
[1] Russian Acad Sci, Pavlov Inst Physiol, St Petersburg 199034, Russia
来源：
BIOLOGY BULLETIN | 2004年 / 31卷 / 03期
关键词：
D O I：
10.1023/B:BIBU.0000030149.79438.93
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Experimental data on the effect of NO synthase inhibition on hemodynamic changes (blood pressure, cardiac output, and peripheral resistance) induced by an increased (polyglucin infusion) or decreased (orthostasis) cardiac output are presented. Under conditions of NO synthase inhibition, the pressor effects of polyglucin and orthostatic hypotension increased by 70 and 72%, respectively. The response of peripheral resistance had a similar trend. Significance of NO secretion by vascular endothelium for the development of systemic hemodynamic responses is proposed.
引用
收藏
页码：277 / 280
页数：4
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