Histopathology and ultrastructure of the liver under combined action of narcotics and hepatitis C and B viruses

被引：0
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作者：
G. I. Nepomnyashchikh
N. P. Tolokonskaya
E. G. Sakharova
S. V. Aidagulova
G. A. Mezentseva
L. M. Nepomnyashchikh
机构：
[1] Siberian Division of the Russian Academy of Medical Sciences,Laboratory of Ultrastructural Bases of Pathology, Institute of Regional Pathology and Pathomorphology
来源：
Bulletin of Experimental Biology and Medicine | 1999年 / 128卷
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摘要：
Liver autopsy material from opioid addicts with viral hepatitis C and C+B showed hepatocyte dystrophy associated with lipid infiltration, hyperplasia of lymphoid tissue, and perivascular fibrosis. Alteration of hepatocytes were most pronounced in patients with hepatitis C+B. Ultrastructure of hepatocytes is characterized by a reduction of protein synthesizing compartment, an increase in volume density of smooth cytoplasmic reticulum, appearance of megamitochondria, and pronounced collagenization of the Disse space.
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页码：963 / 966
页数：3
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