Testing for genetic associations in arbitrarily structured populations

被引:0
|
作者
Minsun Song
Wei Hao
John D Storey
机构
[1] Lewis-Sigler Institute for Integrative Genomics,Department of Molecular Biology
[2] Princeton University,undefined
[3] Center for Statistics and Machine Learning,undefined
[4] Princeton University,undefined
[5] Princeton University,undefined
[6] Present address: Division of Cancer Epidemiology and Genetics,undefined
[7] National Cancer Institute,undefined
[8] US National Institutes of Health,undefined
[9] US Department of Health and Human Services,undefined
[10] Rockville,undefined
[11] Maryland,undefined
[12] USA.,undefined
来源
Nature Genetics | 2015年 / 47卷
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学科分类号
摘要
John Storey and colleagues report a statistical test for genetic association for use with data from structured populations. They demonstrate the use of this test on both simulated data and empirical data from the Northern Finland Birth Cohort, from which they identify significant loci not detected by other methods.
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页码:550 / 554
页数:4
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