Protein function annotation by homology-based inference

被引:0
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作者
Yaniv Loewenstein
Domenico Raimondo
Oliver C Redfern
James Watson
Dmitrij Frishman
Michal Linial
Christine Orengo
Janet Thornton
Anna Tramontano
机构
[1] The Hebrew University of Jerusalem,Department of Biological Chemistry
[2] Sudarsky Center,Department of Biochemical Sciences
[3] University of Rome "La Sapienza",Research Department of Structural and Molecular Biology
[4] University College,Pasteur Institute
[5] European Bioinformatics Institute,Cenci Bolognetti Foundation
[6] Technische Universität,undefined
[7] Helmholtz Zentrum,undefined
[8] German Research Center for Environmental Health,undefined
[9] University of Rome "La Sapienza",undefined
来源
关键词
Protein Data Bank; Function Prediction; Evolutionary Trace; Distribute Annotation System; Protein Structure Initiative;
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摘要
With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.
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