First spin-labeled cytisine derivatives

被引：0
|
作者：
Yu. F. Polienko
V. I. Vinogradova
Sh. Sh. Sagdullaev
N. D. Abdullaev
Yu. V. Gatilov
I. A. Grigor′ev
机构：
[1] Russian Academy of Sciences,N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch
[2] Academy of Sciences of the Republic of Uzbekistan,S. Yu. Yunusov Institute of the Chemistry of Plant Substances
来源：
Chemistry of Natural Compounds | 2013年 / 49卷
关键词：
cytisine; nitroxyl radicals; spin labels; LD50;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Spin-labeled cytisine derivatives containing stable pyrrolidine and piperidine nitroxyl radicals were synthesized by acylation and alkylation of the secondary amine. Toxicological studies showed that introduction of the nitroxyl group decreased significantly the general toxicity.
引用
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页码：311 / 315
页数：4
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