Synthesis, characterization, and pharmacological evaluation of novel azolo- and azinothiazinones containing 2,4-dihydroxyphenyl substituent as anticancer agents

被引:0
|
作者
Joanna Matysiak
Małgorzata Juszczak
Monika M. Karpińska
Ewa Langner
Katarzyna Walczak
Marta Lemieszek
Alicja Skrzypek
Wojciech Rzeski
Andrzej Niewiadomy
机构
[1] University of Life Sciences in Lublin,Department of Chemistry
[2] Institute of Rural Health in Lublin,Department of Medical Biology
[3] Institute of Industrial Organic Chemistry in Warsaw,Department of Pharmacology
[4] Medical University in Lublin,Department of Virology and Immunology
[5] Maria Curie-Skłodowska University in Lublin,undefined
关键词
Azolothiazinones; Resorcinols; Antiproliferative activity; Cytotoxicity; ADMET;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1315 / 1327
页数:12
相关论文
共 50 条
  • [41] Novel 2-Aminobenzothiazole Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents
    Salih, Omar M.
    Al-Sha'er, Mahmoud A.
    Basheer, Haneen A.
    ACS OMEGA, 2024, 9 (12): : 13928 - 13950
  • [42] Synthesis, Characterization and Pharmacological Evaluation of Some Novel 4,5-Dihydro Pyrazole Derivatives Bearing Thiazole and Furan as Potent Antimicrobial and Anticancer Agents
    Munikrishnappa, Chandrashekar Suradhenupura
    Puranik, Sangamesh B.
    Kumar, G. V. Suresh
    Prasad, Y. Rajendra
    RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2016, 7 (04): : 768 - 783
  • [43] Design, synthesis, biological evaluation, molecular docking and QSAR studies of 2,4-dimethylacridones as anticancer agents
    Murahari, Manikanta
    Kharkar, Prashant S.
    Lonikar, Nitin
    Mayur, Y. C.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 130 : 154 - 170
  • [44] Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents
    Vyas, Vivek K.
    Variya, Bhavesh
    Ghate, Manjunath D.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 82 : 385 - 393
  • [45] Synthesis, Characterization, and Biological Evaluation of Novel Thiadiazole-incorporated Aminothiazole Derivatives as Potential Anticancer Agents
    P. Jerupothula
    G. Ravi
    H. Guguloth
    Russian Journal of Organic Chemistry, 2023, 59 : 1407 - 1416
  • [46] Synthesis, Characterization, and Biological Evaluation of Novel Thiadiazole-incorporated Aminothiazole Derivatives as Potential Anticancer Agents
    Jerupothula, P.
    Ravi, G.
    Guguloth, H.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 59 (08) : 1407 - 1416
  • [47] Synthesis and pharmacological evaluation of 2,3-diphenyl acrylonitriles-bearing halogen as selective anticancer agents
    Li, Jia-Jun
    Ma, Jun
    Xin, Ya-Bing
    Quan, Zhe-Shan
    Tian, Yu-Shun
    CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 92 (02) : 1419 - 1428
  • [48] Design, synthesis and evaluation of novel sophoridinic imine derivatives containing conjugated planar structure as potent anticancer agents
    Xu, Yiming
    Jing, Dewang
    Chen, Rui
    Rashid, Haroon Ur
    Jiang, Jun
    Liu, Xu
    Wang, Lisheng
    Xie, Peng
    BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 26 (14) : 4136 - 4144
  • [49] Synthesis and biological evaluation of novel coumarin-chalcone derivatives containing urea moiety as potential anticancer agents
    Kurt, Belma Zengin
    Kandas, Nur Ozten
    Dag, Aydan
    Sonmez, Fatih
    Kucukislamoglu, Mustafa
    ARABIAN JOURNAL OF CHEMISTRY, 2020, 13 (01) : 1120 - 1129
  • [50] Design, synthesis and in vitro evaluation of novel dehydroabietic acid derivatives containing a dipeptide moiety as potential anticancer agents
    Huang, Xiao-Chao
    Jin, Le
    Wang, Meng
    Liang, Dong
    Chen, Zhen-Feng
    Zhang, Ye
    Pan, Ying-Ming
    Wang, Heng-Shan
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 89 : 370 - 385