4-Hydroxy-2-quinolones. 90.* Synthesis and antitubercular activity of 4-methyl-2-thiazolylamides of halo-substituted 4-hydroxy-2-oxo-1,2-dihydro-3- quinolinecarboxylic acids

被引：0
|
作者：
Ukrainets I.V. [1 ]
Sidorenko L.V. [1 ]
Petrushova L.A. [1 ]
Gorokhova O.V. [1 ]
机构：
[1] National Pharmaceutical University
来源：
Chemistry of Heterocyclic Compounds | 2006年 / 42卷 / 1期
关键词：
2-amino-4-methylthiazole; 4-hydroxy-2-oxo-1,2-dihydro-3- quinolinecarboxylic acids; Amides; Antitubercular activity;
D O I：
10.1007/s10593-006-0048-8
中图分类号：
学科分类号：
摘要：
Several variants were studied for the synthesis of esters of halogen derivatives of 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acids, whose reaction with 2-amino-4-methylthiazole gives the corresponding hetarylamides. Results are given for a study of the antitubercular activity of these products. ©2006 Springer Science+Business Media, Inc.
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页码：64 / 69
页数：5
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