Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling

被引：0
|
作者：
Charles McWherter
Yun-Jung Choi
Ramon L. Serrano
Sushil K. Mahata
Robert Terkeltaub
Ru Liu-Bryan
机构：
[1] CymaBay Therapeutics,
[2] Inc.,undefined
[3] VA San Diego Healthcare System,undefined
[4] University of California San Diego,undefined
来源：
Arthritis Research & Therapy | / 20卷
关键词：
Gout; Inflammation; AMPK; Mitochondria; Autophagy flux;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Activation and Signaling by the AMP-Activated Protein Kinase in Endothelial Cells
    Fisslthaler, Beate
    Fleming, Ingrid
    CIRCULATION RESEARCH, 2009, 105 (02) : 114 - 127
  • [22] Activation of the AMP-Activated Protein Kinase Reduces Inflammatory Nociception
    Russe, Otto Quintus
    Moeser, Christine V.
    Kynast, Katharina L.
    King, Tanya S.
    Stephan, Heike
    Geisslinger, Gerd
    Niederberger, Ellen
    JOURNAL OF PAIN, 2013, 14 (11): : 1330 - 1340
  • [23] Activation of AMP-activated protein kinase (AMPK) suppresses cytokine induced inflammatory response in human aortic endothelial cells
    Fdo, Y
    Lan, F
    Cacicedo, JM
    Ruderman, NB
    DIABETES, 2004, 53 : A498 - A498
  • [24] Activation of AMP-activated protein kinase inhibits cardiac myocyte hypertrophy induced by Akt
    Chan, AY
    Soltys, CLM
    Young, ME
    Proud, CG
    Dyck, JR
    CIRCULATION, 2004, 110 (17) : 192 - 192
  • [25] Atorvastatin Inhibits Homocysteine-Induced Endoplasmic Reticulum Stress through Activation of AMP-Activated Protein Kinase
    Jia, Fang
    Wu, Chunfang
    Chen, Zhenyue
    Lu, Guoping
    CARDIOVASCULAR THERAPEUTICS, 2012, 30 (06) : 317 - 325
  • [26] Activation of AMP-Activated Protein Kinase (AMPK) Alleviates Endoplasmic Reticulum (ER) Stress and Inhibits Catabolic Responses to Biomechanical Injury in Chondrocytes
    Petursson, Freyr
    Zhao, Xianling
    Terkeltaub, Robert
    Bryan, Ru L.
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S700 - S701
  • [27] Activation of AMP-activated protein kinase (AMPK) inhibits protein synthesis: a potential strategy to prevent the development of cardiac hypertrophy
    Chan, AYM
    Dyck, JRB
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2005, 83 (01) : 24 - 28
  • [28] 2-Octynoic Acid Inhibits Hepatitis C Virus Infection through Activation of AMP-Activated Protein Kinase
    Yang, Darong
    Xue, Binbin
    Wang, Xiaohong
    Yu, Xiaoyan
    Liu, Nianli
    Gao, Yimin
    Liu, Chen
    Zhu, Haizhen
    PLOS ONE, 2013, 8 (05):
  • [29] AMP-ACTIVATED PROTEIN KINASE (AMPK) DILATES MICROVESSELS VIA ACTIVATION OF THE BKCA CHANNEL
    Schubert, Kai M.
    Schneider, Holger
    Wiedenmann, Margarethe
    Mederos Y Schnitzler, Michael
    Gudermann, Thomas
    Pohl, Ulrich
    JOURNAL OF VASCULAR RESEARCH, 2013, 50 : 57 - 57
  • [30] VASODILATION OF MICROVESSELS BY THE AMP-ACTIVATED PROTEIN KINASE (AMPK) INVOLVES ACTIVATION OF BKCA CHANNELS
    Schubert, Kai M.
    Wiedenmann, Margarete
    Mederos y Schnitzler, Michael
    Gudermann, Thomas
    Pohl, Ulrich
    JOURNAL OF VASCULAR RESEARCH, 2012, 49 : 41 - 41
12345