Oxidation of 5-hydroxy-6-methyluracil with molecular oxygen in the presence of copper(II) chloride in aqueous solution

被引：0
|
作者：
T. R. Nugumanov
A. V. Antipin
S. A. Grabovskii
N. N. Kabal’nova
Yu. I. Murinov
机构：
[1] Russian Academy of Sciences,Institute of Organic Chemistry, Ufa Research Center
来源：
Russian Journal of General Chemistry | 2011年 / 81卷
关键词：
General Chemistry; Uracil; Molecular Oxygen; Donor Center; Potassium Permanganate;
D O I：
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中图分类号：
学科分类号：
摘要：
Oxidation of 5-hydroxy-6-methyluracil with molecular oxygen in the presence of copper(II) chloride involves formation of a 2 : 1 complex with copper(II). The rates of consumption of initial 5-hydroxy-6-methyluracil and oxygen were determined in the temperature range from 40 to 80°C. A probable reaction mechanism implies fixation and activation of molecular oxygen on the copper(II) complex with 5-hydroxy-6-methyluracil with formation of active oxygen species that are responsible for hydroxylation of the double C5=C6 bond in the uracil molecule.
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页码：1543 / 1546
页数：3
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