Application of carbon nanotubes in neurology: clinical perspectives and toxicological risks

被引:0
|
作者
Antonio Nunes
Khuloud Al-Jamal
Takeshi Nakajima
Marwan Hariz
Kostas Kostarelos
机构
[1] University College London,Nanomedicine Laboratory, UCL School of Pharmacy
[2] King’s College London,Institute of Pharmaceutical Sciences, School of Biomedical Sciences
[3] UCL Institute of Neurology,Sobell Department of Motor Neuroscience
[4] UCL Institute of Neurology,Unit of Functional Neurosurgery
来源
Archives of Toxicology | 2012年 / 86卷
关键词
Carbon nanotubes; Neurology; CNS neurotoxicity; Therapy; Neuroregeneration;
D O I
暂无
中图分类号
学科分类号
摘要
Nanomedicine is an emerging field that proposes the application of precisely engineered nanomaterials for the prevention, diagnosis and therapy of certain diseases, including neurological pathologies. Carbon nanotubes (CNT) are a new class of nanomaterials, which have been shown to be promising in different areas of nanomedicine. In this review, the application of CNT interfacing with the central nervous system (CNS) will be described, and representative examples of neuroprosthetic devices, such as neuronal implants and electrodes will be discussed. Furthermore, the possible application of CNT-based materials as regenerative matrices of neuronal tissue and as delivery systems for the therapy of CNS will be presented.
引用
收藏
页码:1009 / 1020
页数:11
相关论文
共 50 条
  • [41] Status and perspectives of clinical neurology in non-university hospitals
    Berlit, P.
    Dommasch, D.
    Heide, W.
    AKTUELLE NEUROLOGIE, 2007, 34 (07) : 396 - +
  • [42] Aggregation behavior of multiwall carbon nanotubes in aqueous and physiological media and their toxicological effects
    Ntim, Susana Addo
    Sae-Khow, Ornthida
    Wang, Xiang
    Tian, Xia
    Witzmann, Frank
    Nel, Andre
    Mitra, Somenath
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [43] POTENTIATING TOXICOLOGICAL INTERACTION OF SINGLE-WALLED CARBON NANOTUBES WITH DISSOLVED METALS
    Al-Shaeri, Majed
    Ahmed, Dina
    McCluskey, Fiona
    Turner, Gavin
    Paterson, Lynn
    Dyrynda, Elisabeth A.
    Hartl, Mark G. J.
    ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2013, 32 (12) : 2701 - 2710
  • [44] A review of exposure and toxicological aspects of carbon nanotubes, and as additives to fire retardants in polymers
    Christou, Antonis
    Stec, Anna A.
    Ahmed, Waqar
    Aschberger, Karin
    Amenta, Valeria
    CRITICAL REVIEWS IN TOXICOLOGY, 2016, 46 (01) : 74 - 95
  • [45] Chemical and Toxicological Evolution of Carbon Nanotubes During Atmospherically Relevant Aging Processes
    Liu, Yongchun
    Liggio, John
    Li, Shao-Meng
    Breznan, Dalibor
    Vincent, Renaud
    Thomson, Errol M.
    Kumarathasan, Premkumari
    Das, Dharani
    Abbatt, Jonathan
    Antinolo, Maria
    Russell, Lynn
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2015, 49 (05) : 2806 - 2814
  • [46] Carbon nanotubes: controlled growth and application
    Liu, Chang
    Cheng, Hui-Ming
    MATERIALS TODAY, 2013, 16 (1-2) : 19 - 28
  • [47] Progress on the application of carbon nanotubes in supercapacitors
    Wu Feng
    Xu Bin
    NEW CARBON MATERIALS, 2006, 21 (02) : 176 - 184
  • [48] Soluble Carbon Nanotubes and Application to Electrochemistry
    Fujigaya, Tsuyohiko
    Tanaka, Yasuhiko
    Nakashima, Naotoshi
    ELECTROCHEMISTRY, 2010, 78 (01) : 2 - 15
  • [49] Field emission and application of carbon nanotubes
    Lim, Seong Chu
    Lee, Kyu
    Lee, Il Ha
    Lee, Young Hee
    NANO, 2007, 2 (02) : 69 - 89
  • [50] Application of Carbon Nanotubes to Nylon Composite
    Suzuki, Tomoko
    Inoue, Sakae
    Nojima, Kazuhiro
    Tsuchimoto, Akiharu
    Chen, Beibei
    Kumar, Mukul
    Ando, Yoshinori
    JAPANESE JOURNAL OF APPLIED PHYSICS, 2011, 50 (01)