Application of carbon nanotubes in neurology: clinical perspectives and toxicological risks

被引:0
|
作者
Antonio Nunes
Khuloud Al-Jamal
Takeshi Nakajima
Marwan Hariz
Kostas Kostarelos
机构
[1] University College London,Nanomedicine Laboratory, UCL School of Pharmacy
[2] King’s College London,Institute of Pharmaceutical Sciences, School of Biomedical Sciences
[3] UCL Institute of Neurology,Sobell Department of Motor Neuroscience
[4] UCL Institute of Neurology,Unit of Functional Neurosurgery
来源
Archives of Toxicology | 2012年 / 86卷
关键词
Carbon nanotubes; Neurology; CNS neurotoxicity; Therapy; Neuroregeneration;
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中图分类号
学科分类号
摘要
Nanomedicine is an emerging field that proposes the application of precisely engineered nanomaterials for the prevention, diagnosis and therapy of certain diseases, including neurological pathologies. Carbon nanotubes (CNT) are a new class of nanomaterials, which have been shown to be promising in different areas of nanomedicine. In this review, the application of CNT interfacing with the central nervous system (CNS) will be described, and representative examples of neuroprosthetic devices, such as neuronal implants and electrodes will be discussed. Furthermore, the possible application of CNT-based materials as regenerative matrices of neuronal tissue and as delivery systems for the therapy of CNS will be presented.
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页码:1009 / 1020
页数:11
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