Cyanamides in cyclization reactions with anthranilates, 2-aminophenyl ketones, and methyl 2-(3-oxopiperazin-2-yl)acetate

被引:0
|
作者
Kh. S. Shikhaliev
A. S. Shestakov
S. M. Medvedeva
N. V. Gusakova
机构
[1] Voronezh State University,
来源
Russian Chemical Bulletin | 2008年 / 57卷
关键词
cyanamides; anthranilic acid; 2-aminophenyl ketones; methyl 2-(3-oxopiperazin-2-yl)acetate; 2-aminoquinazoline; 2-amino-3,4-dihydroquinazolin-4-one; 6-amino-1,3,4,8,9,9a-hexahydro-2; -pyrazino[1,2-; ]pyrimidine-1,8-dione; cyclization;
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摘要
Cyclization of aryl-, aroyl-, and (4,6-dimethylpyrimidin-2-yl)cyanamides with methyl anthranilates, 2-aminophenyl ketones, and methyl 2-(3-oxopiperazin-2-yl)acetate leads to 2-amino-3,4-dihydroquinazolin-4-one, 2-aminoquinazoline, and 6-amino-1,3,4,8,9,9a-hexahydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione derivatives, respectively.
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