Role of abnormal glycosylated IgA1 and interstitial transformation of glomerular endothelial cells in the development and progression of IgA nephropathy

被引：0
|
作者：
Wanyu Jia
Wenjie Dou
Qin Wang
Huiqin Zeng
Peipei Shi
Jing Liu
Zhen Liu
Jin Zhang
Jian-Jiang Zhang
机构：
[1] the First Affiliated Hospital of Zhengzhou University,Department of Pediatrics, Clinical Center of Pediatric Nephrology of Henan Province
[2] Tongji University School of Medicine,Department of Nephrology, Shanghai Tongji Hospital
来源：
Italian Journal of Pediatrics | / 49卷
关键词：
IgA nephropathy; Abnormally glycosylated IgA1; Endothelial cell interstitial transformation; Renal fibrosis; Pathogenesis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] IgA1 molecules produced by tonsillar lymphocytes are under-O-glycosylated in IgA nephropathy
    Horie, A
    Hiki, Y
    Odani, H
    Yasuda, Y
    Takahashi, M
    Kato, M
    Iwase, H
    Kobayashi, Y
    Nakashima, I
    Maeda, K
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2003, 42 (03) : 486 - 496
  • [22] Suppression of Adiponectin by Aberrantly Glycosylated IgA1 in Glomerular Mesangial Cells In Vitro and In Vivo
    Inoue, Tatsuyuki
    Sugiyama, Hitoshi
    Kitagawa, Masashi
    Takiue, Keiichi
    Morinaga, Hiroshi
    Ogawa, Ayu
    Kikumoto, Yoko
    Kitamura, Shinji
    Maeshima, Yohei
    Makino, Hirofumi
    PLOS ONE, 2012, 7 (03):
  • [23] Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity
    Suzuki, Hitoshi
    Fan, Run
    Zhang, Zhixin
    Brown, Rhubell
    Hall, Stacy
    Julian, Bruce A.
    Chatham, W. Winn
    Suzuki, Yusuke
    Wyatt, Robert J.
    Moldoveanu, Zina
    Lee, Jeannette Y.
    Robinson, James
    Tomana, Milan
    Tomino, Yasuhiko
    Mestecky, Jiri
    Novak, Jan
    JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (06): : 1668 - 1677
  • [24] Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy
    Mestecky, J.
    Tomana, M.
    Moldoveanu, Z.
    Julian, B. A.
    Suzuki, H.
    Matousovic, K.
    Renfrow, M. B.
    Novak, L.
    Wyatt, R. J.
    Novak, J.
    KIDNEY & BLOOD PRESSURE RESEARCH, 2008, 31 (01): : 29 - 37
  • [25] Serum under-O-glycosylated IgA1 level is not correlated with glomerular IgA deposition based upon heterogeneity in the composition of immune complexes in IgA nephropathy
    Satake, Kenji
    Shimizu, Yoshio
    Sasaki, Yohei
    Yanagawa, Hiroyuki
    Suzuki, Hitoshi
    Suzuki, Yusuke
    Horikoshi, Satoshi
    Honda, Shinichiro
    Shibuya, Kazuko
    Shibuya, Akira
    Tomino, Yasuhiko
    BMC NEPHROLOGY, 2014, 15
  • [26] Serum under-O-glycosylated IgA1 level is not correlated with glomerular IgA deposition based upon heterogeneity in the composition of immune complexes in IgA nephropathy
    Kenji Satake
    Yoshio Shimizu
    Yohei Sasaki
    Hiroyuki Yanagawa
    Hitoshi Suzuki
    Yusuke Suzuki
    Satoshi Horikoshi
    Shinichiro Honda
    Kazuko Shibuya
    Akira Shibuya
    Yasuhiko Tomino
    BMC Nephrology, 15
  • [27] Capsaicin induces high expression of BAFF and aberrantly glycosylated IgA1 of tonsillar mononuclear cells in IgA nephropathy patients
    Shao, Jing
    Peng, Youming
    He, Liyu
    Liu, Hong
    Chen, Xian
    Peng, Xiaofei
    HUMAN IMMUNOLOGY, 2014, 75 (10) : 1034 - 1039
  • [28] Binding capacity and pathophysiological effects of IgA1 from patients with IgA nephropathy on human glomerular mesangial cells
    Wang, Y
    Zhao, MH
    Zhang, YK
    Li, XM
    Wang, HY
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2004, 136 (01): : 168 - 175
  • [29] Role of endothelial cells in IgA nephropathy
    Yap, HK
    NEPHROLOGY, 1997, 3 (01) : 79 - 84
  • [30] Clinical Significance of the Intensity of Glomerular Galactose-Deficient IgA1 Deposition in IgA Nephropathy
    Nakayama, Maiko
    Suzuki, Hitoshi
    Fukao, Yusuke
    Lee, Mingfeng
    Kano, Toshiki
    Suzuki, Yusuke
    KIDNEY INTERNATIONAL REPORTS, 2022, 7 (12): : 2726 - 2729
12345