Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor

被引：0
|
作者：
Gui-xia Liu
Jin-zhi Tan
Chun-ying Niu
Jian-hua Shen
Xiao-min Luo
Xu Shen
Kai-xian Chen
Hua-liang Jiang
机构：
[1] Center for Drug Discovery and Design,
[2] State Key Laboratory of Drug Research,undefined
[3] Shanghai Institute of Materia Medica,undefined
[4] Shanghai Institutes for Biological Sciences,undefined
[5] Chinese Academy of Sciences,undefined
[6] School of Pharmacy,undefined
[7] East China University of Science and Technology,undefined
来源：
Acta Pharmacologica Sinica | 2006年 / 27卷
关键词：
molecular dynamics simulation; principal component analysis; protein-tyrosine phosphatase 1B; type 2 diabetes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：100 / 110
页数：10
相关论文
共 50 条
  • [31] Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling
    Kabuyama, Yukihito
    Langer, Stephen J.
    Polvinen, Kirsi
    Homma, Yoshimi
    Resing, Katheryn A.
    Ahn, Natalie G.
    MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (08) : 1359 - 1367
  • [32] Molecular Dynamics Simulations and Free Energy Calculations of a Novel Series of Protein Tyrosine Phosphatase 1B Difluoromethylenephosphonic Acid Inhibitors
    Cui Wei
    Zhang Huai
    Ji Ming-Juan
    ACTA PHYSICO-CHIMICA SINICA, 2009, 25 (04) : 668 - 676
  • [33] Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: A paradigm for inhibitor design
    Puius, YA
    Zhao, Y
    Sullivan, M
    Lawrence, DS
    Almo, SC
    Zhang, ZY
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) : 13420 - 13425
  • [34] Protein tyrosine phosphatase 1B in hematopoiesis
    Heinonen, Krista M.
    Tremblay, Michel L.
    CELL CYCLE, 2006, 5 (10) : 1053 - 1056
  • [35] Stearic Acid Serves as a Potent Inhibitor of Protein Tyrosine Phosphatase 1B
    Tsuchiya, Ayako
    Kanno, Takeshi
    Nishizaki, Tomoyuki
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2013, 32 (05) : 1451 - 1459
  • [36] Protein-tyrosine phosphatase 1B mediates the effects of insulin on the actin cytoskeleton in immortalized fibroblasts
    Dadke, S
    Chernoff, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (42) : 40607 - 40611
  • [37] Assessment of protein-tyrosine phosphatase 1B substrate specificity using "inverse alanine scanning"
    Vetter, SW
    Keng, YF
    Lawrence, DS
    Zhang, ZY
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (04) : 2265 - 2268
  • [38] Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin
    Bandyopadhyay, D
    Kusari, A
    Kenner, KA
    Liu, F
    Chernoff, J
    Gustafson, TA
    Kusari, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (03) : 1639 - 1645
  • [39] Essential Role of Protein-tyrosine Phosphatase 1B in the Modulation of Insulin Signaling by Acetaminophen in Hepatocytes
    Ahmed Mobasher, Maysa
    de Toro-Martin, Juan
    Gonzalez-Rodriguez, Agueda
    Ramos, Sonia
    Letzig, Lynda G.
    James, Laura P.
    Muntane, Jordi
    Alvarez, Carmen
    Valverde, Angela M.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (42) : 29406 - 29419
  • [40] Calcium as a mediator between erythropoietin and protein tyrosine phosphatase 1B
    Callero, Mariana A.
    Vota, Daiana M.
    Chamorro, Maria E.
    Wenker, Shirley D.
    Vittori, Daniela C.
    Nesse, Alcira B.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2011, 505 (02) : 242 - 249
12345