The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

被引:0
|
作者
Jens Füllgrabe
Melinda A. Lynch-Day
Nina Heldring
Wenbo Li
Robert B. Struijk
Qi Ma
Ola Hermanson
Michael G. Rosenfeld
Daniel J. Klionsky
Bertrand Joseph
机构
[1] Cancer Centrum Karolinska,Department of Oncology Pathology
[2] Karolinska Institutet,Life Sciences Institute and Departments of Molecular
[3] Stockholm 17176,Department of Neuroscience
[4] Sweden,Department of Medicine
[5] Cellular and Developmental Biology and Biological Chemistry,undefined
[6] University of Michigan,undefined
[7] Ann Arbor,undefined
[8] Karolinska Institutet,undefined
[9] Stockholm 17177,undefined
[10] Sweden,undefined
[11] Howard Hughes Medical Institute,undefined
[12] School of Medicine,undefined
[13] University of California,undefined
[14] San Diego,undefined
[15] La Jolla,undefined
[16] California 92093,undefined
[17] USA,undefined
[18] Graduate Program in Bioinformatics and Systems Biology,undefined
[19] University of California,undefined
[20] San Diego,undefined
[21] La Jolla,undefined
[22] California 92093,undefined
[23] USA,undefined
来源
Nature | 2013年 / 500卷
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摘要
Induction of autophagy is coupled to reduction of histone H4 lysine 16 acetylation through downregulation of the histone acetyltransferase hMOF, showing that histone modifications regulate the outcome of autophagy.
引用
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页码:468 / 471
页数:3
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