Simulation of wagon wheel optical fiber biosensor for quick and easy detection of cancer cells

In this study, a portable micro-structured three-channel plasmonic biosensor was simulated using the finite element method. The main feature of the proposed biosensor was the presence of three resonant wavelengths for a given biomaterial. This feature reduces measurement error as compared with the single-read biosensor. A high refractive index resolution in the order of 10–6 and sensitivity in the order of 105 was calculated for the proposed biosensor. Considering refractive indices of several samples containing cancer cells, such as Jurkat, HeLa, PC12, and MDA-MB-231, which are respectively indicator cells for leukemia, cervical cancer, Adrenal medulla cells, and breast cancer, the three resonant wavelengths were determined for samples. The sensitivity of this biosensor as a function of its length was investigated for a given cancer cell sample.