Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation

被引：0
|
作者：
Larissa Haertle
Tobias Müller
Roy Lardenoije
Anna Maierhofer
Marcus Dittrich
Renzo J. M. Riemens
Samantha Stora
Mathilde Roche
Markus Leber
Steffi Riedel-Heller
Michael Wagner
Martin Scherer
Aimé Ravel
Clotilde Mircher
Cecile Cieuta-Walti
Sophie Durand
Daniel L. A. van de Hove
Per Hoffmann
Alfredo Ramirez
Thomas Haaf
Nady El Hajj
André Mégarbané
机构：
[1] Institute of Human Genetics,Division of Hematology and Oncology, Department of Internal Medicine II
[2] Julius Maximilian University,Department of Bioinformatics
[3] University Hospital,Department of Psychiatry & Neuropsychology, School for Mental Health and Neuroscience (MHeNs)
[4] Julius Maximilian University,Department of Psychiatry and Psychotherapy
[5] Maastricht University,Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy
[6] University Medical Center Göttingen,Department of Neurodegeneration and Geriatric Psychiatry
[7] Institut Jérôme Lejeune,Institute of Social Medicine, Occupational Health and Public Health
[8] CRB BioJeL,Department of Primary Medical Care
[9] University of Cologne,Department of Psychiatry, Psychosomatics and Psychotherapy
[10] Medical Faculty,Institute of Human Genetics
[11] University of Bonn,Department of Genomics, Life & Brain Center
[12] University of Leipzig,Division of Medical Genetics, University Hospital and Department of Biomedicine
[13] German Center for Neurodegenerative Diseases (DZNE),College of Health and Life Sciences
[14] University Medical Centre Hamburg-Eppendorf,undefined
[15] University of Wuerzburg,undefined
[16] University of Bonn,undefined
[17] University of Bonn,undefined
[18] University of Basel,undefined
[19] Hamad Bin Khalifa University,undefined
[20] Education City,undefined
来源：
Clinical Epigenetics | 2019年 / 11卷
关键词：
Trisomy 21; DNA methylation; Intellectual disability; Down syndrome; Cognitive function; Alzheimer’s disease; Infinium Methylation EPIC arrays;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer's disease-related dysregulation
    Haertle, Larissa
    Mueller, Tobias
    Lardenoije, Roy
    Maierhofer, Anna
    Dittrich, Marcus
    Riemens, Renzo J. M.
    Stora, Samantha
    Roche, Mathilde
    Leber, Markus
    Riedel-Heller, Steffi
    Wagner, Michael
    Scherer, Martin
    Ravel, Aime
    Mircher, Clotilde
    Cieuta-Walti, Cecile
    Durand, Sophie
    van de Hove, Daniel L. A.
    Hoffmann, Per
    Ramirez, Alfredo
    Haaf, Thomas
    El Hajj, Nady
    Megarbane, Andre
    CLINICAL EPIGENETICS, 2019, 11 (01)
  • [2] Dysregulation of Alzheimer's disease-related genes and proteins following cardiac arrest
    Pluta, Ryszard
    Ulamek-Koziol, Marzena
    Januszewski, Slawomir
    Czuczwar, Stanislaw J.
    FOLIA NEUROPATHOLOGICA, 2017, 55 (04) : 283 - 288
  • [3] Alzheimer's Disease-Related Lesions
    Alafuzoff, Irina
    JOURNAL OF ALZHEIMERS DISEASE, 2013, 33 : S173 - S179
  • [4] Human Brain and Blood N-Glycome Profiling in Alzheimer's Disease and Alzheimer's Disease-Related Dementias
    Yu, Lei
    Huo, Zhiguang
    Yang, Jingyun
    Palma-Gudiel, Helena
    Boyle, Patricia A.
    Schneider, Julie A.
    Bennett, David A.
    Zhao, Jinying
    FRONTIERS IN AGING NEUROSCIENCE, 2021, 13
  • [5] Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases
    Roubroeks, Janou A. Y.
    Smith, Rebecca G.
    van den Hove, Daniel L. A.
    Lunnon, Katie
    JOURNAL OF NEUROCHEMISTRY, 2017, 143 (02) : 158 - 170
  • [6] Alzheimer’s disease-related dysregulation of mRNA translation causes key pathological features with ageing
    Anshua Ghosh
    Keiko Mizuno
    Sachin S. Tiwari
    Petroula Proitsi
    Beatriz Gomez Perez-Nievas
    Elizabeth Glennon
    Rocio T. Martinez-Nunez
    K. Peter Giese
    Translational Psychiatry, 10
  • [7] Alzheimer's disease-related dysregulation of mRNA translation causes key pathological features with ageing
    Ghosh, Anshua
    Mizuno, Keiko
    Tiwari, Sachin S.
    Proitsi, Petroula
    Gomez Perez-Nievas, Beatriz
    Glennon, Elizabeth
    Martinez-Nunez, Rocio T.
    Giese, K. Peter
    TRANSLATIONAL PSYCHIATRY, 2020, 10 (01)
  • [8] Alzheimer's disease-related cognitive impairment
    Linne, Hannah
    LANCET HEALTHY LONGEVITY, 2021, 2 (09): : E543 - E543
  • [9] Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
    Katie Lunnon
    Rebecca Smith
    Eilis Hannon
    Philip L De Jager
    Gyan Srivastava
    Manuela Volta
    Claire Troakes
    Safa Al-Sarraj
    Joe Burrage
    Ruby Macdonald
    Daniel Condliffe
    Lorna W Harries
    Pavel Katsel
    Vahram Haroutunian
    Zachary Kaminsky
    Catharine Joachim
    John Powell
    Simon Lovestone
    David A Bennett
    Leonard C Schalkwyk
    Jonathan Mill
    Nature Neuroscience, 2014, 17 : 1164 - 1170
  • [10] Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
    Lunnon, Katie
    Smith, Rebecca
    Hannon, Eilis
    De Jager, Philip L.
    Srivastava, Gyan
    Volta, Manuela
    Troakes, Claire
    Al-Sarraj, Safa
    Burrage, Joe
    Macdonald, Ruby
    Condliffe, Daniel
    Harries, Lorna W.
    Katsel, Pavel
    Haroutunian, Vahram
    Kaminsky, Zachary
    Joachim, Catharine
    Powell, John
    Lovestone, Simon
    Bennett, David A.
    Schalkwyk, Leonard C.
    Mill, Jonathan
    NATURE NEUROSCIENCE, 2014, 17 (09) : 1164 - 1170
12345