Studies of Nitric Oxide Production in Rat Tissues in Postnatal Development by Electron Paramagnetic Resonance Spectroscopy

被引：2
|
作者：
Zaripova R.I. [1 ]
Yafarova G.G. [1 ]
Andrianov V.V. [1 ,2 ]
Gainutdinov K.L. [1 ,2 ]
Zefirov T.L. [1 ]
机构：
[1] Kazan Federal University, Kazan
[2] Zavoisky Physical-Technical Institute, Kazan Scientific Center, Russian Academy of Sciences, Kazan
来源：
Biophysics | 2021年 / 66卷 / 3期
关键词：
development; electron paramagnetic resonance; heart; Keywords: nitric oxide; liver; rat;
D O I：
10.1134/S0006350921030234
中图分类号：
学科分类号：
摘要：
Paramagnetic complexes containing nitric oxide (NO) have been assayed in rat heart and liver tissues by EPR spectroscopy to investigate the time variation of NO production during postnatal development. Nitric oxide levels have been assessed from the intensity of a characteristic EPR signal belonging to the (DETC)2–Fe2+–NO complex. The results show that the content of NO in liver tissues increases within the age interval from 28 to 56 days but does not change significantly in postadolescence. In heart tissues, the nitric oxide level increases in adulthood compared to puberty. The NO level in the rat liver is significantly higher than in heart tissues in all studied age groups. © 2021, Pleiades Publishing, Inc.
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页码：487 / 490
页数：3
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