Role of phytocompounds as the potential anti-viral agent: an overview

被引:0
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作者
Swati Sucharita Mohanty
Chita Ranjan Sahoo
Sudhir Kumar Paidesetty
Rabindra Nath Padhy
机构
[1] IMS & Sum Hospital,Department of Medical Oncology
[2] Siksha ‘O’ Anusandhan Deemed to Be University,Central Research Laboratory
[3] IMS & Sum Hospital,Department of Health Research, Ministry of Health & Family Welfare, Govt. of India
[4] Siksha ‘O’ Anusandhan Deemed to Be University,Department of Medicinal Chemistry, School of Pharmaceutical Science
[5] ICMR-Regional Medical Research Centre,undefined
[6] Siksha ‘O’ Anusandhan Deemed to Be University,undefined
关键词
Phytochemicals; Natural product; COVID-19; Antiviral; Viral infection disease; SAR studies;
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摘要
Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines’ developments remain uncanny. In this century of the biological era, human viruses act predominantly as versatile spreaders. The infection of the present COVID-19 virus is up in the air; blithely, the integument of medicinal chemistry approaches, particularly bioactive derived phytocompounds could be helpful to control those human viruses, recognized in the last 100 years. Indeed, natural products are being used for various therapeutic purposes. The major bioactive phytocompounds are chemically containing coumarin, thiosulfonate, steroid, polysaccharide, tannin, lignin, proanthocyanidin, terpene, quinone, saponin, flavonoid, alkaloid, and polyphenol, that are documented for inhibitory action against several viral infections. Mostly, about 20–30% of plants from tropical or temperate regions are known to have some antiviral activity. This comprehensive analysis of bioactive-derived phytocompounds would represent a significant impact and might be helpful for antiviral research and the current state of viral treatments.
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页码:2311 / 2329
页数:18
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