Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling

被引:0
|
作者
Randolph S Ashton
Anthony Conway
Chinmay Pangarkar
Jamie Bergen
Kwang-Il Lim
Priya Shah
Mina Bissell
David V Schaffer
机构
[1] University of California Berkeley,Department of Chemical and Biomolecular Engineering
[2] Lawrence Berkeley National Laboratory,Life Sciences Division
[3] Present address: Department of Biomedical Engineering,undefined
[4] Wisconsin Institutes for Discovery,undefined
[5] University of Wisconsin Madison,undefined
[6] Madison,undefined
[7] Wisconsin,undefined
[8] USA (R.S.A.),undefined
[9] Department of Medical and Pharmaceutical Sciences,undefined
[10] College of Science,undefined
[11] Sookmyung Women's University,undefined
[12] Seoul,undefined
[13] Korea (K.-I.L.).,undefined
来源
Nature Neuroscience | 2012年 / 15卷
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学科分类号
摘要
This work shows that ephrin-B2 from astrocytes provides a critical niche signal for cell fate determination in adult mouse hippocampus, in part by directing neuronal differentiation of adult neural stem cells through EphB4-dependent juxtacrine signaling.
引用
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页码:1399 / 1406
页数:7
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