Metabolism and Pharmacokinetics of Selective Serotonin Reuptake Inhibitors

被引:0
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作者
C. Lindsay DeVane
机构
[1] Medical University of South Carolina,Department of Psychiatry and Behavioral Sciences
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关键词
selective serotonin reuptake inhibitors; metabolism; pharmacokinetics; fluoxetine; fluvoxamine; paroxetine; sertraline; citalopram; cytochrome P450;
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学科分类号
摘要
1. Five drugs with the predominant pharmacologic effect of inhibiting the neuronal reuptake of serotonin are available worldwide for clinical use. This class of psychoactive drugs, known as selective serotonin reuptake inhibitors (SSRIs), is comprised of fluoxetine, sertraline, paroxetine, fluvoxamine, and citalopram.
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页码:443 / 466
页数:23
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