How does Plasmodium falciparum stick to CSA? Let's see in the crystal

被引：0

作者：

Graham A Bentley

Benoît Gamain

机构：

[1] Graham A. Bentley is at the Institut Pasteur,

[2] Unité d'Immunologie Structurale,undefined

[3] Centre National de la Recherche Scientifique URA2185,undefined

[4] F-75724 Paris Cedex 15,undefined

[5] France. bentley@pasteur.fr,undefined

[6] Benoît Gamain is at the Institut Pasteur,undefined

[7] Unité de Biologie des Interactions Hôte-Parasite,undefined

[8] Centre National de la Recherche Scientifique URA2581,undefined

[9] F-75724 Paris Cedex 15,undefined

[10] France. bgamain@pasteur.fr,undefined

来源：

Nature Structural & Molecular Biology | 2008年 / 15卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The crystal structure of the CSA-binding Duffy-binding-like domain DBL3x of the VAR2CSA-encoded PfEMP1 adhesin has been solved in the free state and complexed with CSA oligosaccharides, shedding light on the major host-parasite interaction in pregnancy-associated malaria.

引用

页码：895 / 897

页数：2

共 18 条

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