Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis

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作者
Niranjan Jeganathan
Dan Predescu
Jin Zhang
Fei Sha
Cristina Bardita
Monal Patel
Stephen Wood
Jeffrey A. Borgia
Robert A. Balk
Sanda Predescu
机构
[1] Rush University Medical Center and Rush Medical College,Division of Pulmonary and Critical Care Medicine
[2] Rush University,Department of Pharmacology and Division of Pulmonary and Critical Care Medicine
[3] Rush University,Department of Pharmacology
[4] Rush University,Department of Pharmacology
[5] Rush University,Department of Immunology
[6] Rush University,Department of Biochemistry
[7] Rush University Medical Center and Rush Medical College,Division of Pulmonary and Critical Care Medicine
[8] Rush University Medical Center and Rush Medical College,Department of Pharmacology and Division of Pulmonary and Critical Care Medicine
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关键词
Lung cancer; Cell migration; Cell proliferation; E3 ubiquitin ligase; Rac1; RhoA; Tumor metastasis; Intersectin-1s; mSos1; Eps8; Cbl;
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