Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease

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Matthew Ackers-Johnson
Wilson Lek Wen Tan
Roger Sik-Yin Foo
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[1] National University Health System,Cardiovascular Research Institute
[2] Genome Institute of Singapore,undefined
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The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and failings, of the heart.
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