Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease

被引:0
|
作者
Matthew Ackers-Johnson
Wilson Lek Wen Tan
Roger Sik-Yin Foo
机构
[1] National University Health System,Cardiovascular Research Institute
[2] Genome Institute of Singapore,undefined
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and failings, of the heart.
引用
收藏
相关论文
共 50 条
  • [1] Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
    Ackers-Johnson, Matthew
    Tan, Wilson Lek Wen
    Foo, Roger Sik-Yin
    NATURE COMMUNICATIONS, 2018, 9
  • [2] Single-Cell RNA Sequencing and Combinatorial Approaches for Understanding Heart Biology and Disease
    Wang, Le
    Jin, Bo
    BIOLOGY-BASEL, 2024, 13 (10):
  • [3] The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease
    Slenders, Lotte
    Tessels, Danielle E.
    van der Laan, Sander W.
    Pasterkamp, Gerard
    Mokry, Michal
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [4] Single-Cell RNA Sequencing: Unravelling the Bone One Cell at a Time
    Ryan C. Chai
    Current Osteoporosis Reports, 2022, 20 : 356 - 362
  • [5] Single-Cell RNA Sequencing: Unraveling the Brain One Cell at a Time
    Ofengeim, Dimitry
    Giagtzoglou, Nikolaos
    Huh, Dann
    Zou, Chengyu
    Yuan, Junying
    TRENDS IN MOLECULAR MEDICINE, 2017, 23 (06) : 563 - 576
  • [6] Single-Cell RNA Sequencing: Unravelling the Bone One Cell at a Time
    Chai, Ryan C.
    CURRENT OSTEOPOROSIS REPORTS, 2022, 20 (05) : 356 - 362
  • [7] Review of Single-Cell RNA Sequencing in the Heart
    Yamada, Shintaro
    Nomura, Seitaro
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (21) : 1 - 15
  • [8] Unraveling asthma through single-cell RNA sequencing in understanding disease mechanisms
    Yuan, Xingxing
    Li, Chaofan
    Yang, Liuxin
    Gao, Jiawei
    Wang, Bingyu
    Li, Zhuying
    JOURNAL OF ASTHMA, 2025,
  • [9] Applications of single-cell RNA sequencing in rheumatoid arthritis
    Figueiredo, Marxa L.
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [10] Applications of Single-Cell RNA Sequencing in Cardiovascular Research
    Fan, Yu
    Zhou, Han
    Liu, Xuexue
    Li, Jingyan
    Xu, Ke
    Fu, Xiaodong
    Ye, Lei
    Li, Guang
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 9