Two New 5-Oxomilbemycins Possessing an Unusual 3,27-Epoxy Bond from the Genetically Engineered Strain Streptomyces bingchenggensis BCJ60

被引：0
|
作者：
Zhi-Kui Hao
Jian-Song Li
Ji-Dong Wang
Wen-Sheng Xiang
Hai-Yan Wang
机构：
[1] Institute of Applied Biotechnology,Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science
[2] School of Medicine and Pharmaceutical Engineering,Life Science and Biotechnology Research Center, School of Life Science
[3] Taizhou Vocational and Technical College,undefined
[4] Huzhou University,undefined
[5] Northeast Agricultural University,undefined
来源：
Chemistry of Natural Compounds | 2021年 / 57卷
关键词：
genetically engineered strain; BCJ60; milbemycin derivatives; acaricidal and nematocidal activities;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two undescribed milbemycin derivatives, milbemycin P (1) and milbemycin Q (2), were isolated from a culture of the genetically engineered strain Streptomyces bingchenggensis BCJ60. Their structures were elucidated through the interpretation of NMR and HR-ESI-MS spectroscopic data, as well as comparison with previous reports. Their acaricidal and nematocidal activities against Tetranychus cinnabarinus and Bursaphelenchus xylophilus were tested. The results showed that compounds 1–2 possessed potent acaricidal and nematocidal activities.
引用
收藏
页码：289 / 292
页数：3
相关论文
共 6 条
  • [1] Two New 5-Oxomilbemycins Possessing an Unusual 3,27-Epoxy Bond from the Genetically Engineered Strain Streptomyces bingchenggensis BCJ60
    Hao, Zhi-Kui
    Li, Jian-Song
    Wang, Ji-Dong
    Xiang, Wen-Sheng
    Wang, Hai-Yan
    CHEMISTRY OF NATURAL COMPOUNDS, 2021, 57 (02) : 289 - 292
  • [2] New 5-oxomilbemycins from a Genetically Engineered Strain Streptomyces bingchenggensis BCJ60
    Li, Jiansong
    Zhang, Hui
    Zhang, Shaoyong
    Wang, Haiyan
    Zhang, Ji
    Chen, Anliang
    Wang, Jidong
    Xiang, Wensheng
    RECORDS OF NATURAL PRODUCTS, 2017, 11 (05) : 431 - 438
  • [3] New milbemycin metabolites from the genetically engineered strain Streptomyces bingchenggensis BCJ60
    Li, Jian-Song
    Du, Min-Na
    Zhang, Hui
    Zhang, Ji
    Zhang, Shao-Yong
    Wang, Hai-Yan
    Chen, An-Liang
    Wang, Ji-Dong
    Xiang, Wen-Sheng
    NATURAL PRODUCT RESEARCH, 2017, 31 (07) : 780 - 784
  • [4] Isolation and identification of new macrocyclic lactones from a genetically engineered strain Streptomyces bingchenggensis BCJ60
    Li, Jiansong
    Zhang, Shaoyong
    Zhang, Hui
    Wang, Haiyan
    Zhang, Ji
    Chen, Anliang
    Wang, Jidong
    Xiang, Wensheng
    JOURNAL OF ANTIBIOTICS, 2017, 70 (03): : 297 - 300
  • [5] Isolation and identification of new macrocyclic lactones from a genetically engineered strain Streptomyces bingchenggensis BCJ60
    Jiansong Li
    Shaoyong Zhang
    Hui Zhang
    Haiyan Wang
    Ji Zhang
    Anliang Chen
    Jidong Wang
    Wensheng Xiang
    The Journal of Antibiotics, 2017, 70 : 297 - 300
  • [6] New macrocyclic lactones with acaricidal and nematocidal activities from a genetically engineered strain Streptomyces bingchenggensis BCJ60
    Li, Jian-Song
    Zhang, Hui
    Zhang, Shao-Yong
    wang, Hai-Yan
    Zhang, Ji
    Chen, An-Liang
    Wang, Ji-Dong
    Xiang, Wen-Sheng
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 19 (04) : 339 - 346
1