Whole-genome and whole-exome sequencing in neurological diseases

被引：0
|
作者：
Jia-Nee Foo
Jian-Jun Liu
Eng-King Tan
机构：
[1] Human Genetics,Department of Neurology
[2] Genome Institute of Singapore,undefined
[3] A*STAR,undefined
[4] National Neuroscience Institute,undefined
[5] Duke-National University of Singapore Graduate Medical School,undefined
[6] Singapore General Hospital,undefined
来源：
Nature Reviews Neurology | 2012年 / 8卷
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摘要：
Next-generation sequencing approaches are becoming increasingly affordable for use in the clinical setting, and have the potential to provide valuable insights into the genetic underpinnings of complex neurological diseases. In this Review, Foo et al. discuss how whole-genome and whole-exome sequencing data can be deciphered, and consider how such data might be used for diagnosis and risk prediction in the neurology clinic.
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页码：508 / 517
页数：9
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