Synthesis and mechanism of formation of 5-benzylidene-2-thioxo-2,3-dihydro-(1H,5H)-pyrimidine-4,6-diones difluoromethoxy derivatives

被引：0
|
作者：
A. I. Rakhimov
I. Yu. Kameneva
S. A. Avdeev
R. G. Fedunov
机构：
[1] Volgograd State Technical University,Institute of Chemical Problems in Ecology
[2] Russian Academy of Natural Sciences,undefined
来源：
Russian Journal of General Chemistry | 2011年 / 81卷
关键词：
General Chemistry; Dihydro; Pyrimidine Ring; Difluoro; Polar Hydrogen Atom;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Reactions of 5-benzylidene-2-thioxo-2,3-dihydro-(1H,5H)-pyrimidine-4,6-diones with a singlet difluorocarbene afford difluoromethoxy derivatives in 20–34% yield. The quantum-chemical analysis of the reaction mechanism showed that N,N-dimethylformamide is involved into the formation of difluoromethoxy derivatives.
引用
收藏
相关论文
共 50 条
  • [31] BENZAZEPINES .5. FURTHER STUDIES ON 2,3-DIHYDRO-1H[1,5] BENZODIAZEPINES AND 2,3-DIHYDRO-[1,5]BENZOTHIAZEPINES
    HIDEG, K
    HIDEGHAN.O
    ACTA CHIMICA ACADEMIAE SCIENTARIUM HUNGARICAE, 1973, 75 (02): : 137 - 160
  • [32] Synthesis and reactivity of 2,3-dihydro-1H-2,3-benzodiazepine-1,4(5H)-dione
    Bihel, Frederic J. -J.
    Hellal, Malik
    Bourguignon, Jean-Jacques
    SYNTHESIS-STUTTGART, 2007, (24): : 3791 - 3796
  • [33] 5-[[[ARYLAMINO]METHYL][ARYLMETHYLENE]]DIHYDRO-1-ARYL-3-(4-PHENYL-2-THIAZOLYL)-2-THIOXO-4,6-(1H,5H)PYRIMIDINEDIONES AND THEIR ANTIPARKINSONIAN ACTIVITY
    NAITHANI, PK
    SRIVASTAVA, VK
    GUPTA, TK
    SHANKER, K
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1991, 68 (07) : 422 - 424
  • [34] INDOLE AND QUINOLINE DERIVATIVES OF "2,3-DIHYDRO-1-BENZOTHIEPIN-4(5H)ONE
    PELLICCIARI, R
    NATALINI, B
    RICCI, A
    ALUNNIBISTOCCHI, G
    DEMEO, G
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1978, 15 (06) : 927 - 928
  • [35] SYNTHESIS AND HYDROLYSIS OF 5-HALO-2,3-DIHYDRO-1,3-6H-OXAZINE-2,6-DIONES
    FARKAS, J
    FLIEGEROVA, O
    SKODA, J
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1976, 41 (07) : 2059 - 2072
  • [36] A Catalyst-Free Aqueous Synthesis of 2-Amino-7,9-dihydrothieno[3,2:5,6]pyrido[2,3-d]pyrimidine-4,6(3H,5H)-dione Derivatives
    Yao, Changsheng
    Lu, Ting
    Yu, Chenxia
    Wang, Xiangshan
    Li, Tuanjie
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 : E163 - E166
  • [37] 5-butyl-6-methyl-2-thioxo-2,3-dihydro-pyrimidin-4(1H)-one
    Long, T
    Zhou, HB
    Wu, AX
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O2169 - O2171
  • [38] Convergent Domino Knoevenagel Hetero-Diels-Alder and Domino Oxidation Hetero-Diels-Alder Reactions Encountered in an Unexpected Formation of Novel 5-Aryl-1H-pyrano[2,3-d]pyrimidine-2,4(3H,5H)-diones and 5-Aryl-2,3-dihydro-2-thioxo-1H-pyrano[2,3-d]pyrimidin-4(5H)-ones
    Zidar, Nace
    Kikelj, Danijel
    HELVETICA CHIMICA ACTA, 2011, 94 (05) : 859 - 867
  • [39] Synthesis of 2,3-Dihydro-4(1H)-quinoline Derivatives
    Chemistry of Heterocyclic Compounds, 1996, 32 (04)
  • [40] Synthesis of 2,3-dihydro-4(1H)-quinolinone derivatives
    Mickevichius, VJ
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1996, (04): : 523 - 526
12345