UV-Absorbing Substance in the Red Alga Porphyra yezoensis (Bangiales, Rhodophyta) Block Thymine Photodimer Production

被引：0
|
作者：
Taku Misonou
Junko Saitoh
Saori Oshiba
Yukiko Tokitomo
Miyuki Maegawa
Yukio Inoue
Hirokazu Hori
Takeki Sakurai
机构：
[1] Yamanashi University,Department of Ecosocial System Engineering, Faculty of Engineering
[2] Kofu,Department of Biology, Faculty of Education
[3] Yamanashi 400-8511,Department of Food Science, Faculty of Education and Human Sciences
[4] Yamanashi University,Department of Marine Biological Science, Faculty of Bioresources
[5] Kofu,Department of Electrical Engineering, Faculty of Engineering
[6] Yamanashi 400-8510,undefined
[7] Yamanashi University,undefined
[8] Kofu,undefined
[9] Yamanashi 400-8510,undefined
[10] Mie University,undefined
[11] Tsu,undefined
[12] Mie 514-8507,undefined
[13] Yamanashi University,undefined
[14] Kofu,undefined
[15] Yamanashi 400-8511,undefined
来源：
Marine Biotechnology | 2003年 / 5卷
关键词：
DNA lesion; mycosporine-like amino acid; photodimer production; thymine; UV-absorbing substance;
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学科分类号：
摘要：
The effect of the water-soluble UV-absorbing substance (UVAS) extracted from the marine red alga Porphyra yezoensis Ueda on UV-dependent thymine photodimer production was investigated. The T<>T pyrimidine-pyrimidone 6-4 dimer and the cyclobutane cis-syn T<>T 5-6 dimer produced by UV irradiation with a xenon lamp were analyzed by reverse-phase high-performance liquid chromatography. Although the dimer production was reduced when the irradiation was filtered through a UVAS solution, it decreased more when thymine was mixed with UVAS. Furthermore, UVAS inhibited the degradation of UV-irradiated thymine. The inhibitory effect of UVAS was significantly greater than that of exogenously added adenine or guanine, which forms complementary base pairs with thymine. These data suggest that in addition to its filtering effect against UV radiation, UVAS also protects thymine by a direct molecule-to-molecule energy transfer process. The protective function of UVAS against UV irradiation is advantageous for this alga under strong UV irradiation.
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页码：194 / 200
页数：6
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