Pulling together to improve stability

被引:0
|
作者
Cody J. Higginson
Phillip B. Messersmith
机构
[1] University of California,Department of Materials Science and Engineering
[2] University of California,Department of Bioengineering, Department of Materials Science and Engineering
[3] Lawrence Berkeley National Laboratory,Materials Sciences Division
来源
Nature Chemistry | 2019年 / 11卷
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学科分类号
摘要
Maleimide–thiol adducts are popular in both bioconjugation and materials chemistry, however, they are unstable under physiological conditions. Now, a mechanochemical approach uses pulling forces to stabilize maleimide–thiol adducts and improve the stability of polymer–protein conjugates.
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页码:295 / 296
页数:1
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