Pulling together to improve stability

被引：0
|
作者：
Cody J. Higginson
Phillip B. Messersmith
机构：
[1] University of California,Department of Materials Science and Engineering
[2] University of California,Department of Bioengineering, Department of Materials Science and Engineering
[3] Lawrence Berkeley National Laboratory,Materials Sciences Division
来源：
Nature Chemistry | 2019年 / 11卷
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摘要：
Maleimide–thiol adducts are popular in both bioconjugation and materials chemistry, however, they are unstable under physiological conditions. Now, a mechanochemical approach uses pulling forces to stabilize maleimide–thiol adducts and improve the stability of polymer–protein conjugates.
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页码：295 / 296
页数：1
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