Benefits and Challenges of Rare Genetic Variation in Alzheimer’s Disease

被引：0
|
作者：
Detelina Grozeva
Salha Saad
Georgina E. Menzies
Rebecca Sims
机构：
[1] Cardiff University,Division of Psychological Medicine and Clinical Neuroscience, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine
[2] Cardiff University,UK Dementia Research Institute at Cardiff, School of Medicine
来源：
Current Genetic Medicine Reports | 2019年 / 7卷
关键词：
Alzheimer’s disease; Genetics; Susceptibility; Rare variants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：53 / 62
页数：9
相关论文
共 50 条
  • [31] Challenge accepted: uncovering the role of rare genetic variants in Alzheimer's disease
    Khani, Marzieh
    Gibbons, Elizabeth
    Bras, Jose
    Guerreiro, Rita
    MOLECULAR NEURODEGENERATION, 2022, 17 (01)
  • [32] Genetic variation in Clusterin gene and Alzheimer's disease risk in Han Chinese
    Yu, Jin-Tai
    Ma, Xiao-Ying
    Wang, Ying-Li
    Sun, Lei
    Tan, Lin
    Hu, Nan
    Tan, Lan
    NEUROBIOLOGY OF AGING, 2013, 34 (07) : 1921.e17 - 1921.e23
  • [33] Genetic variation in α1-antichymotrypsin and its association with Alzheimer's disease
    Wang, XY
    DeKosky, ST
    Luedecking-Zimmer, E
    Ganguli, M
    Kamboh, MI
    HUMAN GENETICS, 2002, 110 (04) : 356 - 365
  • [34] Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease
    Zahratka, Jeffrey A.
    Shao, Yvonne
    Shaw, McKenzie
    Todd, Kaitlin
    Formica, Shane V.
    Khrestian, Maria
    Montine, Thomas
    Leverenz, James B.
    Bekris, Lynn M.
    NEUROBIOLOGY OF AGING, 2017, 51 : 43 - 53
  • [35] Genetic variation in α1-antichymotrypsin and its association with Alzheimer’s disease
    Xiaoyan Wang
    Steven T. DeKosky
    Erin Luedecking-Zimmer
    Mary Ganguli
    Ilyas M. Kamboh
    Human Genetics, 2002, 110 : 356 - 365
  • [36] Genetic variation in the renin-angiotensin system and risk of Alzheimer's disease
    Gustafson, D
    Eriksson, E
    Blennow, K
    Skoog, I
    NEUROBIOLOGY OF AGING, 2004, 25 : S501 - S502
  • [37] Apolipoprotein E genetic variation and Alzheimer's Disease - A meta-analysis
    Rubinsztein, DC
    Easton, EF
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2000, 11 (04) : 238 - 238
  • [38] Genetic variation in the renin-angiotensin system and risk of Alzheimer's disease
    Gustafson, D
    Eriksson, E
    Blennow, K
    Skoog, I
    AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 2004, 130B (01): : 15 - 16
  • [39] A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease
    Papassotiropoulos, A
    Bagli, M
    Kurz, A
    Kornhuber, J
    Förstl, H
    Maier, W
    Pauls, J
    Lautenschlager, N
    Heun, R
    ANNALS OF NEUROLOGY, 2000, 47 (03) : 399 - 403
  • [40] Apolipoprotein E genetic variation and Alzheimer's disease - A meta-analysis
    Rubinsztein, DC
    Easton, DF
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 1999, 10 (03) : 199 - 209
12345