Association between obesity and a polymorphism in the β1-adrenoceptor gene (Gly389Arg ADRB1) in Caucasian women

被引:0
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作者
IJ Dionne
MJ Garant
AA Nolan
TI Pollin
DG Lewis
AR Shuldiner
ET Poehlman
机构
[1] Clinical Pharmacology and Metabolic Research Unit,Department of Medicine
[2] University of Vermont,Division of Endocrinology, Department of Medicine
[3] Diabetes and Nutrition,Département de Nutrition
[4] and Baltimore Veterans Administration Geriatric Research and Education Clinical Center,undefined
[5] University of Maryland,undefined
[6] Research Center on Aging,undefined
[7] Geriatric Institute of University of Sherbrooke,undefined
[8] Faculté de Médecine,undefined
[9] Université de Montréal,undefined
来源
关键词
body weight; body mass index; fat mass; energy balance; genetics;
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学科分类号
摘要
Introduction: Genetic variants affecting adrenoceptors have been suggested to influence body fatness. A putative gain-of-function polymorphism in the β1-adrenoceptor was recently discovered (Gly389Arg ADRB1). We examined the association between Gly389Arg ADRB1 and obesity status in a large cohort of well-characterized individuals.
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页码:633 / 639
页数:6
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