Reactions of cinnoline, cinnoline N-oxides, and their chloro derivatives with alkylamines: The first case of nucleophilic substitution of hydrogen in the cinnoline series

被引：0

作者：

Buluchevskaya, N.A. ^{[1
]}

Gulevskaya, A.V. ^{[1
]}

Pozharskii, A.F. ^{[1
]}

机构：

[1] Rostov State University, Rostov-on-Don 344090, Russia

来源：

Chemistry of Heterocyclic Compounds | 2003年 / 39卷 / 01期

关键词：

3-alkylaminocinnoline - 4-alkylaminocinnoline - 4-chlorocinnoline N(1)-oxide; 4-chlorocinnoline N(2)-oxide; cinnoline; cinnoline N(1)-oxide; cinnoline N(2)-oxide; aminodehalogenation - Alkylamine - Chloro derivatives - Cinnoline - N-Oxides - Nucleophilic substitutions;

D O I：

10.1023/A:1023076810168

中图分类号：

学科分类号：

摘要：

In contrast to cinnoline and cinnoline N(1)-oxide, cinnoline N(2)-oxide reacts with primary and secondary amines on prolonged heating or in the presence of oxidants to give 3-alkylaminocinnolines.

引用

页码：87 / 95

页数：8

共 25 条

[21] Formation of derivatives of benzofuran, indole, and cinnoline in the reaction of 7-(N-morpholinyl)-7-methyl-8a-hydroxy-4,5,8,8a-tetrahydro-7H-pyrrolo[3,2-e]-2,1, 3-benzoxadiazole 6-oxide with nucleophilic reagents
Samsonov V.A.
Volodarskii L.B.
Chemistry of Heterocyclic Compounds, 1998, 34 (3) : 271 - 274
[22] REACTIONS OF ORGANIC-ANIONS .81. AROMATIC NUCLEOPHILIC-SUBSTITUTION OF CHLORINE AND NITRO-GROUP IN 4-CHLOROPYRIDINE AND 4-NITROPYRIDINE N-OXIDES BY CARBANIONS DERIVED FROM 2-PHENYLALKANENITRILES
JAWDOSIUK, M
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POLISH JOURNAL OF CHEMISTRY, 1979, 53 (03) : 617 - 621
[23] NUCLEOPHILIC DISPLACEMENTS IN SUBSTITUTED PYRIDINE N-OXIDES .2. KINETICS OF REACTIONS BETWEEN PIPERIDINE AND 2- AND 4-BROMO-,4-CHLORO-, AND 2- AND 4-NITRO-PYRIDINE 1-OXIDE IN ANHYDROUS ETHANOL
JOHNSON, RM
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[24] The First Case of an Aryl Imination Reaction by Direct Nucleophilic Substitution of Hydrogen: Synthesis of 2-arylimino Derivatives for 1,2-dihydro-1-methyl-5(6,7,8)-nitroquinolines
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Demidov, Oleg P.
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Avakyan, Elena K.
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Borovlev, Ivan V.
CHEMISTRYSELECT, 2025, 10 (08):
[25] NUCLEOPHILIC DISPLACEMENTS IN SUBSTITUTED PYRIDINE N-OXIDES .I. KINETICS OF REACTIONS BETWEEN SODIUM ETHOXIDE AND 2- AND 4-BROMO-4-CHLORO-,2-,3 AND 4-NITRO-,4-CHLORO-3,5-DIMETHYL-, AND 3,5-DIMETHYL-4-NITRO-PYRIDINE 1-OXIDE IN ANHYDROUS ETHANOL
JOHNSON, RM
JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC, 1966, (11): : 1058 - &

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