MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome

被引：0
|
作者：
J C Hassel
A Sucker
L Edler
H Kurzen
I Moll
C Stresemann
K Spieth
C Mauch
K Rass
R Dummer
D Schadendorf
机构：
[1] Skin Cancer Unit,Department of Biostatistics
[2] German Cancer Research Center,Department of Epigenetics
[3] University Hospital Mannheim,Department of Dermatology
[4] German Cancer Research Center,Department of Dermatology
[5] German Cancer Research Center,Department of Dermatology
[6] Johann Wolfgang Goethe-University,Department of Dermatology
[7] University of Cologne,Department of Dermatology
[8] Saarland University Hospital,undefined
[9] University Hospital Zurich,undefined
[10] University Hospital Essen,undefined
[11] Hufelandstr. 55,undefined
[12] Bayer-Schering,undefined
[13] Müllerstr. 178,undefined
来源：
British Journal of Cancer | 2010年 / 103卷
关键词：
MGMT; gene methylation; melanoma; therapy toxicity; temozolomide;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：820 / 826
页数：6
相关论文
共 50 条
  • [1] MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome
    Hassel, J. C.
    Sucker, A.
    Edler, L.
    Kurzen, H.
    Moll, I.
    Stresemann, C.
    Spieth, K.
    Mauch, C.
    Rass, K.
    Dummer, R.
    Schadendorf, D.
    BRITISH JOURNAL OF CANCER, 2010, 103 (06) : 820 - 826
  • [2] Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy
    Dunn, J.
    Baborie, A.
    Alam, F.
    Joyce, K.
    Moxham, M.
    Sibson, R.
    Crooks, D.
    Husband, D.
    Shenoy, A.
    Brodbelt, A.
    Wong, H.
    Liloglou, T.
    Haylock, B.
    Walker, C.
    BRITISH JOURNAL OF CANCER, 2009, 101 (01) : 124 - 131
  • [3] Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy
    J Dunn
    A Baborie
    F Alam
    K Joyce
    M Moxham
    R Sibson
    D Crooks
    D Husband
    A Shenoy
    A Brodbelt
    H Wong
    T Liloglou
    B Haylock
    C Walker
    British Journal of Cancer, 2009, 101 : 124 - 131
  • [4] MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma
    Donson, Andrew M.
    Addo-Yobo, Steven O.
    Handler, Michael H.
    Gore, Lia
    Foreman, Nicholas K.
    PEDIATRIC BLOOD & CANCER, 2007, 48 (04) : 403 - 407
  • [5] MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma
    Donson, A. M.
    Addo-Yobo, S. O.
    Handler, M. H.
    Gore, L.
    Foreman, N. K.
    NEURO-ONCOLOGY, 2007, 9 (02) : 189 - 189
  • [6] MGMT gene promotor methylation does not predict temozolomide response in melanoma
    Hassel, J. C.
    Sucker, A.
    Edler, L.
    Rausch, R.
    Kurzen, H.
    Moll, I.
    Stresemann, C.
    Lyko, F.
    Spieth, K.
    Egberts, F.
    Dummer, R.
    Schadendorf, D.
    EXPERIMENTAL DERMATOLOGY, 2009, 18 (03) : 301 - 301
  • [7] Temozolomide Treatment for Aggressive Pituitary Tumors: Correlation of Clinical Outcome with O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation and Expression
    Bush, Zachary M.
    Longtine, Janina A.
    Cunningham, Tracy
    Schiff, David
    Jane, John A., Jr.
    Vance, Mary Lee
    Thorner, Michael O.
    Laws, Edward R., Jr.
    Lopes, M. Beatriz S.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (11): : E280 - E290
  • [8] The Impact of MGMT Promoter Methylation and Temozolomide Treatment in Serbian Patients with Primary Glioblastoma
    Jovanovic, Nikola
    Mitrovic, Tatjana
    Cvetkovic, Vladimir J.
    Tosic, Svetlana
    Vitorovic, Jelena
    Stamenkovic, Slavisa
    Nikolov, Vesna
    Kostic, Aleksandar
    Vidovic, Natasa
    Krstic, Miljan
    Jevtovic-Stoimenov, Tatjana
    Pavlovic, Dusica
    MEDICINA-LITHUANIA, 2019, 55 (02):
  • [9] Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide
    K A van Nifterik
    J van den Berg
    W F van der Meide
    N Ameziane
    L E Wedekind
    R D M Steenbergen
    S Leenstra
    M V M Lafleur
    B J Slotman
    L J A Stalpers
    P Sminia
    British Journal of Cancer, 2010, 103 : 29 - 35
  • [10] Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide
    van Nifterik, K. A.
    van den Berg, J.
    van der Meide, W. F.
    Ameziane, N.
    Wedekind, L. E.
    Steenbergen, R. D. M.
    Leenstra, S.
    Lafleur, M. V. M.
    Slotman, B. J.
    Stalpers, L. J. A.
    Sminia, P.
    BRITISH JOURNAL OF CANCER, 2010, 103 (01) : 29 - 35
12345