Peptidergic Regulation of Thymocyte Differentiation, Proliferation, and Apoptosis during Aging of the Thymus

被引:0
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作者
N. S. Lin’kova
V. O. Polyakova
A. V. Trofimov
I. M. Kvetnoy
V. Kh. Khavinson
机构
[1] North Western Division of the Russian Academy of Medical Sciences,St. Petersburg Institute of Bioregulation and Gerontology
关键词
geroprotective peptides; proliferation; apoptosis; differentiation; thymocytes;
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摘要
The effects of T-31, AB-17, and AB-9 peptides on old (passage 8) thymocyte culture were studied. Only AB-9 peptide exhibited a complex geroprotective effect on thymocytes during their aging. Peptide AB-9 stimulated proliferative activity and differentiation of thymocytes and inhibited their apoptosis.
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页码:239 / 242
页数:3
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