Is Iron Accumulation a Possible Risk Factor for Sarcopenia?

被引：0
|
作者：
Guoyang Zhao
机构：
[1] The Affiliated Hospital of Jiangsu University,Department of Orthopaedics
来源：
Biological Trace Element Research | 2018年 / 186卷
关键词：
Sarcopenia; Iron accumulation; Skeletal muscle; Ferritin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Sarcopenia has a high incidence among the elderly, with significant negative effects on the quality of life. The pathogenesis of sarcopenia is complex, and many factors are involved in its development and progression. Sarcopenia might be associated with iron accumulation given that (1) age-related iron accumulation was found in the skeletal muscle, (2) excess iron could cause skeletal muscle damage or atrophy, and (3) patients with sarcopenia showed higher levels of serum ferritin. Understanding the etiology and pathogenesis of sarcopenia would help to develop new treatment and preventive methods, thereby improving the quality of life of the elderly patients.
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页码：379 / 383
页数：4
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