Design, Synthesis, In Vitro Cytotoxicity, ADME Prediction, and Molecular Docking Study of Benzimidazole-Linked Pyrrolone and N-Benzylpyrrolone Derivatives

被引:0
|
作者
A. Husain
M. Bhutani
S. Parveen
S. A. Khan
A. Ahmad
M. A. Iqbal
机构
[1] Department of Pharmaceutical Chemistry,
[2] School of Pharmaceutical Education and Research,undefined
[3] Jamia Hamdard,undefined
[4] Chemistry Department,undefined
[5] Faculty of Science,undefined
[6] Taibah University,undefined
[7] Yanbu Branch,undefined
[8] Department of Chemistry,undefined
[9] School of Chemical and Life Sciences,undefined
[10] Jamia Hamdard,undefined
[11] College of Pharmacy,undefined
[12] National University of Science and Technology,undefined
[13] Health Information Technology Department,undefined
[14] Faculty of Applied Studies,undefined
[15] King Abdulaziz University,undefined
来源
Russian Journal of Organic Chemistry | 2022年 / 58卷
关键词
heterocyclics; pyrrolone; anticancer activity; VEGFR-2; molecular docking;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1438 / 1450
页数:12
相关论文
共 50 条
  • [31] Acetylcholine Inhibitory Study of Novel Thio Linked Coumarin-Benzimidazole Derivatives: Design, Synthesis, Computational, and In Silico Molecular Docking Studies
    T. H. Maruthi Nayaka
    Itte Pushpavathi
    Y. R. Pavithra
    Russian Journal of Bioorganic Chemistry, 2024, 50 : 211 - 226
  • [32] Synthesis, α-glycosidase inhibitory potential and molecular docking study of benzimidazole derivatives
    Taha, Muhammad
    Rahim, Fazal
    Zaman, Khalid
    Selvaraj, Manikandan
    Uddin, Nizam
    Farooq, Rai Khalid
    Nawaz, Muhammad
    Sajid, Muhammad
    Nawaz, Faisal
    Ibrahim, Mohamad
    Khan, Khalid Mohammed
    BIOORGANIC CHEMISTRY, 2020, 95
  • [33] Acetylcholine Inhibitory Study of Novel Thio Linked Coumarin-Benzimidazole Derivatives: Design, Synthesis, Computational, and In Silico Molecular Docking Studies
    Nayaka, T. H. Maruthi
    Pushpavathi, Itte
    Nagesh, Y. R.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2024, 50 (01) : 211 - 226
  • [34] Synthesis, in vitro α-amylase, α-glucosidase activities and molecular docking study of new benzimidazole bearing thiazolidinone derivatives
    Khan, Shoaib
    Ullah, Hayat
    Rahim, Fazal
    Nawaz, Mohsan
    Hussain, Rafaqat
    Rasheed, Liaqat
    JOURNAL OF MOLECULAR STRUCTURE, 2022, 1269
  • [35] Design, docking study and ADME prediction of Isatin derivatives as anti-HIV agents
    Pawar, Vidya S.
    Lokwani, Deepak K.
    Bhandari, Shashikant V.
    Bothara, Kailash G.
    Chitre, Trupti S.
    Devale, Titiksh L.
    Modhave, Nileema S.
    Parikh, Jignesh K.
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (03) : 370 - 380
  • [36] Synthesis, Molecular Docking Studies and ADME Prediction of Some New Albendazole Derivatives as α-Glucosidase Inhibitors
    Senkardes, Sevil
    Kulabas, Necla
    Kucukguzel, S. Guniz
    ACTA CHIMICA SLOVENICA, 2022, 69 (03) : 526 - 535
  • [37] Design, synthesis, anticancer screening, docking studies and in silico ADME prediction of some β-carboline derivatives
    Abdelsalam, Mohamed A.
    AboulWafa, Omaima M.
    Badawey, El-Sayed A. M.
    El-Shoukrofy, Mai S.
    El-Miligy, Mostafa M.
    Gouda, Noha
    Elaasser, Mahmoud M.
    FUTURE MEDICINAL CHEMISTRY, 2018, 10 (10) : 1159 - 1175
  • [38] Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies
    Ye, Jiqing
    Yang, Xiao
    Xu, Min
    Chan, Paul Kay-sheung
    Ma, Cong
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 182
  • [39] Design, Synthesis, Cytotoxicity, and Molecular Docking Studies of New Benzimidazole Hybrids as Possible Anticancer Agents
    Mishra, Shashank Shekher
    Sharma, C. S.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2021, 31 (01) : 21 - 29
  • [40] Synthesis of hydrazine containing piperazine or benzimidazole derivatives and their potential as α-amylase inhibitors by molecular docking, inhibition kinetics and in vitro cytotoxicity activity studies
    Ummuhan Cakmak
    Fulya Oz-Tuncay
    Serap Basoglu-Ozdemir
    Elif Ayazoglu-Demir
    İlke Demir
    Ahmet Colak
    Selcen Celik-Uzuner
    Safiye Sag Erdem
    Nuri Yildirim
    Medicinal Chemistry Research, 2021, 30 : 1886 - 1904