Bin classification of G-protein-coupled peptide receptors

被引:0
|
作者
Henri Moereels
Paul J. Lewi
Frits Daeyaert
Paul A.J. Janssen
机构
[1] Center for Molecular Design,
[2] Janssen Research Foundation,undefined
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关键词
binmap; counting residues; sequence consistency;
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摘要
With the use of the binmap method, 154 G-protein-coupled peptide receptors are classified. The binmap coordinates are obtained by using the number of residues between the conserved N residue in TM1 and C in the TM4-TM5 loop, between this C and the conserved P in TM6, and between this P and the last residue of the sequence. The binmap suggests that the cloned fMLP receptor in rabbit belongs in fact to the IL8 receptor type.
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页码:139 / 142
页数:3
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