Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301)

被引：0
|
作者：
Keisuke Miwa
Eiji Oki
Masanobu Enomoto
Keisuke Ihara
Koji Ando
Fumihiko Fujita
Masahiro Tominaga
Shinichiro Mori
Goro Nakayama
Mototsugu Shimokawa
Hiroshi Saeki
Hideo Baba
Masaki Mori
Yoshito Akagi
机构：
[1] Kurume University Hospital,Multidisciplinary Treatment Cancer Center
[2] Kyushu University,Department of Surgery and Science, Graduate School of Medical Sciences
[3] Tokyo Medical University,Gastrointestinal and Pediatric Surgery
[4] Dokkyo Medical University,First Department of Surgery
[5] Kurume University School of Medicine,Department of Surgery
[6] Department of Gastroenterological Surgery,Department of Digestive Surgery, Breast and Thyroid Surgery
[7] Hyogo Cancer Center,Department of Gastroenterological Surgery, Graduate School of Medicine
[8] Kagoshima University,Cancer Biostatistics Laboratory, Clinical Research Institute
[9] Nagoya University,Department of Biostatistics
[10] National Hospital Organization Kyusyu Cancer Center,Department of Gastroenterological Surgery
[11] Yamaguchi University Graduate School of Medicine,Department of Gastroenterological Surgery
[12] Gunma University Graduate School of Medicine,undefined
[13] Kumamoto University Graduate School of Medicine,undefined
来源：
BMC Cancer | / 21卷
关键词：
Rectal cancer; Neoadjuvant chemotherapy; Chemoradiotherapy; SOX; mFOLFOX6;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] Neoadjuvant FLOT versus SOX phase II randomized clinical trial for patients with locally advanced gastric cancer
    Birendra Kumar Sah
    Benyan Zhang
    Huan Zhang
    Jian Li
    Fei Yuan
    Tao Ma
    Min Shi
    Wei Xu
    Zhenglun Zhu
    Wentao Liu
    Chao Yan
    Chen Li
    Bingya Liu
    Min Yan
    Zhenggang Zhu
    Nature Communications, 11
  • [32] Neoadjuvant FLOT versus SOX phase II randomized clinical trial for patients with locally advanced gastric cancer
    Sah, Birendra Kumar
    Zhang, Benyan
    Zhang, Huan
    Li, Jian
    Yuan, Fei
    Ma, Tao
    Shi, Min
    Xu, Wei
    Zhu, Zhenglun
    Liu, Wentao
    Yan, Chao
    Li, Chen
    Liu, Bingya
    Yan, Min
    Zhu, Zhenggang
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [33] A phase II, randomised study of mFOLFOX6 with or without the Akt inhibitor ipatasertib in patients with locally advanced or metastatic gastric or gastroesophageal junction cancer
    Bang, Y-J
    Kang, Y-K
    Ng, M.
    Chung, H. C.
    Wainberg, Z. A.
    Gendreau, S.
    Chan, W. Y.
    Xu, N.
    Maslyar, D.
    Meng, R.
    Chau, I
    Ajani, J. A.
    EUROPEAN JOURNAL OF CANCER, 2019, 108 : 17 - 24
  • [34] Randomized phase III trial comparing preoperative versus postoperative radiotherapy with capecitabine in locally advanced rectal cancer
    Park, J.
    Ybon, S.
    Choi, E.
    Kim, Y.
    Kim, J.
    Yu, C.
    Kim, T.
    Chang, H.
    Jang, S.
    Kim, J.
    EJC SUPPLEMENTS, 2009, 7 (02): : 330 - 330
  • [35] Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study
    Sun, Pei-Long
    Li, Bing
    Ye, Qi-Fa
    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2012, 27 (10) : 1325 - 1332
  • [36] Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study
    Pei-Long Sun
    Bing Li
    Qi-Fa Ye
    International Journal of Colorectal Disease, 2012, 27 : 1325 - 1332
  • [37] A multi-center randomized controlled trial of mFOLFOX6 with or without radiation in neoadjuvant treatment of local advanced rectal cancer (FOWARC study): Preliminary results.
    Deng, Yanhong
    Chi, Pan
    Lan, Ping
    Wang, Lei
    Cui, Long
    Chen, Daoda
    Cao, Jie
    Wei, Hongbo
    Peng, Xiang
    Huang, Zonghai
    Cai, Guangfu
    Zhao, Ren
    Huang, Zhongcheng
    Luo, Yiding
    Zhang, Yuxin
    Cai, Yue
    Wang, Jianping
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [38] Efficacy and safety of different radiotherapy doses in neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: A retrospective study
    Xu, Yuyan
    Zou, Haizhou
    Shao, Zhenyong
    Zhang, Xuebang
    Ren, XiaoLin
    He, Huijuan
    Zhang, Dahai
    Du, Dexi
    Zou, Changlin
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [39] Apatinib plus SOX regimen as neoadjuvant chemotherapy for locally advanced gastric cancer: A phase II study.
    Zheng, Ya'nan
    Yang, Xiao
    Shi, Hongpeng
    Yang, Zhongyin
    Yan, Chao
    Ni, Zhentian
    Li, Mengjiao
    Sah, Birendra Kumar
    Liu, Wentao
    Xu, Wei
    Yao, Xuexin
    Zhu, Zhenglun
    Yan, Min
    Zhu, Zhenggang
    Li, Chen
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [40] Phase II study of preoperative 5-fluorouraciloxaliplatin chemotherapy and radiotherapy in locally advanced rectal cancer
    Pucci, Francesca
    Bui, Simona
    Camisa, Roberta
    Negri, Francesca
    Leonardi, Francesco
    Martinelli, Roberto
    Losardo, Pier Luigi
    Roncoroni, Luigi
    Dell'Abate, Paolo
    Anselmi, Elisa
    Crafa, Pellegrino
    Cascinu, Stefano
    Ardizzoni, Andrea
    ANNALS OF ONCOLOGY, 2007, 18 : 21 - 21
12345