Oral intake of bucillamine, carvedilol, metformin, or phenformin does not protect against UVR-induced squamous cell carcinomas in hairless mice

被引:0
|
作者
Celina Pihl
Peter Bjerring
Flemming Andersen
Merete Haedersdal
Catharina M. Lerche
机构
[1] Copenhagen University Hospital–Bispebjerg and Frederiksberg,Department of Dermatology
[2] University of Copenhagen,Department of Pharmacy
[3] Aalborg University Hospital,Department of Dermatology
[4] Private Hospital Molholm,Department of Dermatology
[5] University of Copenhagen,Department of Clinical Medicine
关键词
Ultraviolet radiation; Skin cancer; Drug repurposing; Hairless mice; Photoprotection;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:517 / 526
页数:9
相关论文
共 20 条
  • [11] Protective Effect of Topical Brimonidine Administration on UVR-Induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Albino Hairless Mice
    Bouvier, G.
    Learn, D.
    Nonne, C.
    Feraille, G.
    Vial, E.
    Ruty, B.
    INTERNATIONAL JOURNAL OF TOXICOLOGY, 2016, 35 (01) : 80 - 81
  • [12] Genetic deletion of TNFα in mice inhibits UVR-induced development of cutaneous squamous cell carcinomas via suppression of its own receptors and associated signals to epidermal cell survival
    Singh, Ashok
    Singh, Anupama
    Bauer, Samuel J.
    Verma, Ajit K.
    CANCER RESEARCH, 2015, 75
  • [13] Furocoumarin-induced epidermal melanogenesis does not protect against skin photocarcinogenesis in hairless mice
    Kipp, C
    Lewis, EJ
    Young, AR
    PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1998, 67 (01) : 126 - 132
  • [14] Metformin Prevents the Development of Oral Squamous Cell Carcinomas from Carcinogen-Induced Premalignant Lesions
    Vitale-Cross, Lynn
    Molinolo, Alfredo A.
    Martin, Daniel
    Younis, Rania H.
    Maruyama, Takashi
    Patel, Vyomesh
    Chen, Wanjun
    Schneider, Abraham
    Gutkind, J. Silvio
    CANCER PREVENTION RESEARCH, 2012, 5 (04) : 562 - 573
  • [15] Therapeutic and immune effects of 5-aminolevulinic acid photodynamic therapy on UVB-induced squamous cell carcinomas in hairless mice
    Wang, Hongwei
    Li, Jingjing
    Lv, Ting
    Tu, Qingfeng
    Huang, Zheng
    Wang, Xiuli
    EXPERIMENTAL DERMATOLOGY, 2013, 22 (05) : 362 - 363
  • [16] PHOTORADIATION AT 670 nm DOES NOT INFLUENCE UVB-INDUCED SQUAMOUS CELL CARCINOMA IN HAIRLESS MICE TREATED AFTER TUMOR INDUCTION
    Lanzafame, Raymond
    Myakishev, Max
    Stadler, Istvan
    Bennett, M.
    Zavislan, James
    LASERS IN SURGERY AND MEDICINE, 2009, : 61 - 62
  • [17] Budesonide, a corticosteroid, and bexarotene, a retinoid X receptor-selective ligand, synergistically inhibit ultraviolet B-induced squamous cell carcinomas (SCCs) in SKH-1 hairless mice
    Tang, X
    Kim, AL
    Huaijie, Z
    Kopelovich, L
    Athar, M
    Bickers, DR
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 124 (04) : A25 - A25
  • [18] β-cell specific overexpression of suppressor of cytokine signalling-3 does not protect against multiple low dose streptozotocin induced type 1 diabetes in mice
    Borjesson, A.
    Ronn, S. G.
    Karlsen, A. E.
    Billestrup, N.
    Sandler, S.
    IMMUNOLOGY LETTERS, 2011, 136 (01) : 74 - 79
  • [19] Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB irradiation Harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice
    Kramata, P
    Lu, YP
    Lou, YR
    Singh, RN
    Kwon, SM
    Conney, AH
    CANCER RESEARCH, 2005, 65 (09) : 3577 - 3585
  • [20] PROTECTION AGAINST MALIGNANT CONVERSION OF CHEMICALLY-INDUCED BENIGN SKIN PAPILLOMAS TO SQUAMOUS-CELL CARCINOMAS IN SENCAR MICE BY A POLYPHENOLIC FRACTION ISOLATED FROM GREEN TEA
    KATIYAR, SK
    AGARWAL, R
    MUKHTAR, H
    CANCER RESEARCH, 1993, 53 (22) : 5409 - 5412