What do we measure when we measure cell-associated HIV RNA

被引：0
|
作者：
Alexander O. Pasternak
Ben Berkhout
机构：
[1] Academic Medical Center of the University of Amsterdam,Laboratory of Experimental Virology, Department of Medical Microbiology
来源：
Retrovirology | / 15卷
关键词：
Cell-associated HIV RNA; Virological biomarker; HIV persistence; HIV reservoir; Antiretroviral therapy; HIV cure;
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摘要：
Cell-associated (CA) HIV RNA has received much attention in recent years as a surrogate measure of the efficiency of HIV latency reversion and because it may provide an estimate of the viral reservoir size. This review provides an update on some recent insights in the biology and clinical utility of this biomarker. We discuss a number of important considerations to be taken into account when interpreting CA HIV RNA measurements, as well as different methods to measure this biomarker.
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