This review focuses on behavioral genetic studies of sweet, umami, bitter and salt taste responses in mammals. Studies involving mouse inbred strain comparisons and genetic analyses, and their impact on elucidation of taste receptors and transduction mechanisms are discussed. Finally, the effect of genetic variation in taste responsiveness on complex traits such as drug intake is considered. Recent advances in development of genomic resources make behavioral genetics a powerful approach for understanding mechanisms of taste.
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UNIV LONDON,INST PSYCHIAT,GENET & DEV PSYCHIAT RES CTR,LONDON WC1E 7HU,ENGLANDUNIV LONDON,INST PSYCHIAT,GENET & DEV PSYCHIAT RES CTR,LONDON WC1E 7HU,ENGLAND
McClearn, GE
Vogler, GP
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UNIV LONDON,INST PSYCHIAT,GENET & DEV PSYCHIAT RES CTR,LONDON WC1E 7HU,ENGLANDUNIV LONDON,INST PSYCHIAT,GENET & DEV PSYCHIAT RES CTR,LONDON WC1E 7HU,ENGLAND
Vogler, GP
Plomin, R
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UNIV LONDON,INST PSYCHIAT,GENET & DEV PSYCHIAT RES CTR,LONDON WC1E 7HU,ENGLANDUNIV LONDON,INST PSYCHIAT,GENET & DEV PSYCHIAT RES CTR,LONDON WC1E 7HU,ENGLAND