Autophagosomes form at ER–mitochondria contact sites

被引:0
|
作者
Maho Hamasaki
Nobumichi Furuta
Atsushi Matsuda
Akiko Nezu
Akitsugu Yamamoto
Naonobu Fujita
Hiroko Oomori
Takeshi Noda
Tokuko Haraguchi
Yasushi Hiraoka
Atsuo Amano
Tamotsu Yoshimori
机构
[1] Graduate School of Medicine,Department of Genetics
[2] Osaka University,Department of Oral Frontier Biology
[3] 2-2 Yamadaoka,Department of Cell Biology
[4] Suita,Department of Preventive Dentistry
[5] Osaka 565-0871,undefined
[6] Japan,undefined
[7] Laboratory of Intracellular Membrane Dynamics,undefined
[8] Graduate School of Frontier Biosciences,undefined
[9] Osaka University,undefined
[10] 2-2 Yamadaoka,undefined
[11] Suita,undefined
[12] Osaka 565-0871,undefined
[13] Japan,undefined
[14] Center for Oral Frontier Science,undefined
[15] Osaka University Graduate School of Dentistry,undefined
[16] 1-8 Yamadaoka,undefined
[17] Suita,undefined
[18] Osaka 565-0871,undefined
[19] Japan,undefined
[20] National Institute of Information and Communications Technology,undefined
[21] 588-2 Iwaoka,undefined
[22] Iwaoka-cho,undefined
[23] Nishi-ku,undefined
[24] Kobe 651-2492,undefined
[25] Japan,undefined
[26] Nuclear Dynamics Group,undefined
[27] Graduate School of Frontier Biosciences,undefined
[28] Osaka University,undefined
[29] 1-3 Yamadaoka,undefined
[30] Suita,undefined
[31] Osaka 565-0871,undefined
[32] Japan,undefined
[33] Faculty of Bio-Science,undefined
[34] Nagahama Institute of Bio-Science and Technology,undefined
[35] 1266 Tamura-cho,undefined
[36] Nagahama,undefined
[37] Shiga 526-0829,undefined
[38] Japan,undefined
[39] Research Institute for Microbial Diseases,undefined
[40] Osaka University,undefined
[41] 3-1 Yamadaoka,undefined
[42] Suita,undefined
[43] Osaka 565-0871,undefined
[44] Japan,undefined
[45] Osaka University Graduate School of Dentistry,undefined
[46] 1-8 Yamadaoka,undefined
[47] Suita,undefined
[48] Osaka 565-0871,undefined
[49] Japan,undefined
来源
Nature | 2013年 / 495卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
This study shows that autophagosomes form at sites of contact between the endoplasmic reticulum and mitochondria, and that formation requires the SNARE protein syntaxin 17.
引用
收藏
页码:389 / 393
页数:4
相关论文
共 50 条
  • [31] Pannexin 2 localization at ER-mitochondria contact sites sensitizes cells to apoptosis.
    Le Vasseur, M.
    Vogl, A.
    Naus, C. C.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [32] Crosstalk between mitochondria-ER contact sites and the apoptotic machinery as a novel health meter
    Larranaga-SanMiguel, Alvaro
    Bengoa-Vergniory, Nora
    Flores-Romero, Hector
    TRENDS IN CELL BIOLOGY, 2025, 35 (01) : 33 - 45
  • [33] Impaired Mitochondrial Metabolism And Er-Mitochondria Contact Sites Affect Signaling In Cancer Cells
    Zaltron, Elisabetta
    Severin, Filippo
    Ruzza, Alessia
    Vianello, Federica
    Palazzo, Alberta
    Brillo, Valentina
    Leanza, Luigi
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2024, 1865 : 97 - 97
  • [34] Impaired mitochondrial metabolism and ER-mitochondria contact sites affect signaling in cancer cells
    Severin, Filippo
    Elisabetta, Zaltron
    Alessia, Ruzza
    Valentina, Brillo
    Marisa, Brini
    Tito, Cali
    Luigi, Leanza
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2024, 1870 (08): : 27 - 27
  • [35] ER-Mitochondria contact sites: A new regulator of cellular calcium flux comes into play
    Krols, Michiel
    Bultynck, Geert
    Janssens, Sophie
    JOURNAL OF CELL BIOLOGY, 2016, 214 (04): : 367 - 370
  • [36] Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites
    Peter, Arun T. John
    Herrmann, Beatrice
    Antunes, Diana
    Rapaport, Doron
    Dimmer, Kai Stefan
    Kornmann, Benoit
    JOURNAL OF CELL BIOLOGY, 2017, 216 (10): : 3219 - 3229
  • [37] The role of PERK-E-Syt1 interaction in mitochondria homeostasis and lipid trafficking at the ER-mitochondria contact sites
    Sassano, Maria Livia
    Van Vliet, Alex R.
    Van Eygen, Sofie
    Derua, Rita
    Dehairs, Jonas
    Swinnen, Johan
    Pinton, Paolo
    Agostinis, Patrizia
    CELL DEATH DISCOVERY, 2019, 5
  • [38] MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites
    Takeda, Keisuke
    Nagashima, Shun
    Shiiba, Isshin
    Uda, Aoi
    Tokuyama, Takeshi
    Ito, Naoki
    Fukuda, Toshifumi
    Matsushita, Nobuko
    Ishido, Satoshi
    Iwawaki, Takao
    Uehara, Takashi
    Inatome, Ryoko
    Yanagi, Shigeru
    EMBO JOURNAL, 2019, 38 (15):
  • [39] ER-Golgi contact sites
    De Matteis, M. A.
    FEBS OPEN BIO, 2021, 11 : 20 - 20
  • [40] MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites
    Hertlein, Vanessa
    Flores-Romero, Hector
    Das, Kushal K.
    Fischer, Sebastian
    Heunemann, Michael
    Calleja-Felipe, Maria
    Knafo, Shira
    Hipp, Katharina
    Harter, Klaus
    Fitzgerald, Julia C.
    Garcia-Saez, Ana J.
    LIFE SCIENCE ALLIANCE, 2020, 3 (01)