Spotlight on Dabigatran Etexilate in the Prevention of Stroke and Systemic Embolism in Patients with Atrial Fibrillation

被引：0
|
作者：
Karly P. Garnock-Jones
机构：
[1] Adis,
[2] a Wolters Kluwer Business,undefined
来源：
Drugs & Aging | 2011年 / 28卷
关键词：
Atrial Fibrillation; Warfarin; Dabigatran; Major Bleeding; Haemorrhagic Stroke;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The need for safe, effective and easily administered and monitored anti-thrombotic treatments that do not have the issues common to warfarin treatment has led to the development of new anticoagulant drugs. Dabigatran etexilate (Pradaxa®, Pradax™) is a prodrug of the direct thrombin inhibitor dabigatran, a direct, reversible, potent inhibitor of thrombin. Dabigatran does not interact with food, and is associated with very few known drug interactions.
引用
收藏
页码：415 / 419
页数：4
相关论文
共 50 条
  • [41] Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation
    Blair, Hannah A.
    Keating, Gillian M.
    [J]. DRUGS, 2017, 77 (03) : 331 - 344
  • [42] Apixaban reduces stroke or systemic embolism in patients with atrial fibrillation
    不详
    [J]. BRITISH JOURNAL OF HOSPITAL MEDICINE, 2011, 72 (09) : 491 - 491
  • [43] Treatments for stroke prevention in atrial fibrillation: A network meta-analysis and indirect comparisons versus dabigatran etexilate
    Roskell, Neil S.
    Lip, Gregory Y. H.
    Noack, Herbert
    Clemens, Andreas
    Plumb, Jonathan M.
    [J]. THROMBOSIS AND HAEMOSTASIS, 2010, 104 (06) : 1106 - 1115
  • [44] New oral anticoagulants in stroke and systemic embolism prevention in patients suffering from atrial fibrillation
    Sleszycka, Justyna
    Demkow, Marcin
    [J]. POSTEPY W KARDIOLOGII INTERWENCYJNEJ, 2011, 7 (03): : 242 - 247
  • [45] Dabigatran is a new option for stroke prevention in atrial fibrillation
    Lyon, Sue
    [J]. BRITISH JOURNAL OF HOSPITAL MEDICINE, 2009, 70 (10) : 559 - 559
  • [46] Hemopericardium under dabigatran for stroke prevention in atrial fibrillation
    Stoellberger, Claudia
    Heger, Maria
    Finsterer, Josef
    [J]. BLOOD COAGULATION & FIBRINOLYSIS, 2017, 28 (02) : 185 - 188
  • [47] Dabigatran for Stroke Prevention in Patients with TIA or Ischaemic Stroke and Atrial Fibrillation: Practical Apects
    Diener, H. C.
    Grond, M.
    Roether, J.
    Veltkamp, R.
    Weber, R.
    Weimar, C.
    Hohnloser, S. H.
    [J]. AKTUELLE NEUROLOGIE, 2011, 38 (05) : 261 - 266
  • [48] Dabigatran Compared With Warfarin for Stroke Prevention in Atrial Fibrillation
    Berg, Alan M.
    [J]. ANNALS OF INTERNAL MEDICINE, 2011, 154 (08) : 570 - 570
  • [49] Pharmacoeconomic Analysis of Dabigatran Etexilate Effectiveness in Patients With Nonvalvular Atrial Fibrillation
    Belousov, Yu. B.
    Mareev, V. Yu.
    Yavelov, I. S.
    Belousov, D. YU.
    Afanasieva, E. V.
    [J]. KARDIOLOGIYA, 2012, 52 (01) : 44 - 51
  • [50] Dabigatran efficacy-safety assessment for stroke prevention in patients with atrial fibrillation
    Eikelboom, J. W.
    Quinlan, D. J.
    Connolly, S. J.
    Hart, R. G.
    Yusuf, S.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2012, 10 (05) : 966 - 968
12345